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Tbio
CD300C
CMRF35-like molecule 6

Protein Summary
Description
The CMRF35 antigen, which was identified by reactivity with a monoclonal antibody, is present on monocytes, neutrophils, and some T and B lymphocytes (Jackson et al., 1992 [PubMed 1349532]).[supplied by OMIM, Mar 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000330793
  • ENSP00000329507
  • ENSG00000167850

Symbol
  • CMRF35
  • CMRF35A
  • CMRF35A1
  • IGSF16
  • LIR
  • CLM-6
  • CMRF35
  • IGSF16
  • CMRF-35
  • CMRF35A
  • CMRF-35A
  • CMRF35A1
  • CMRF35-A1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
tissue sample
0.69
disease perturbation
0.62
protein domain
0.58
transcription factor perturbation
0.54
gene perturbation
0.48


Related Tools
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 291.62   (req: < 5)
Gene RIFs: 7   (req: <= 3)
Antibodies: 245   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 291.62   (req: >= 5)
Gene RIFs: 7   (req: > 3)
Antibodies: 245   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (5)
1 – 5 of 5
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
CD300c molecule
VGNC:9174
468320
Mouse
MGI:2153249
140497
Horse
CMRF35-like molecule 6
100630791
Cow
CMRF35-like molecule 6
526163
Pig
CD300c molecule
100514248
Species
Name
OMA
EggNOG
Inparanoid
Chimp
CD300c molecule
Mouse
Horse
CMRF35-like molecule 6
Cow
CMRF35-like molecule 6
Pig
CD300c molecule
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q08708-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Pathways (3)
Adaptive Immune System (R-HSA-1280218)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Adaptive Immune System
Reactome
Immune System
Reactome
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Name
Explore in Pharos
Explore in Source
Adaptive Immune System
Immune System
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Gene Ontology Terms (6)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Traceable Author Statement (TAS)
ProtInc
Protein-Protein Interactions (101)
1 – 10 of 101
FAM210A
Tdark
Novelty: 0.2598101
p_int: 0.917266937
p_ni: 0.082733063
Score: 0.692
Data Source: BioPlex,STRINGDB
ATP12A
Tchem
Family: Transporter
Novelty: 0.00008793
p_int: 0.899054351
p_ni: 0.100945649
Score: 0.219
Data Source: BioPlex,STRINGDB
LILRB1
Tbio
Novelty: 0.00463824
Score: 0.833
Data Source: STRINGDB
LILRA1
Tdark
Novelty: 0.17371827
Score: 0.824
Data Source: STRINGDB
LILRA2
Tbio
Novelty: 0.05598199
Score: 0.824
Data Source: STRINGDB
TYROBP
Tbio
Family: Enzyme
Novelty: 0.00410031
Score: 0.801
Data Source: STRINGDB
NBR1
Tbio
Novelty: 0.00893066
Score: 0.796
Data Source: STRINGDB
MAP1LC3B
Tbio
Novelty: 0.00101276
Score: 0.777
Data Source: STRINGDB
LILRB4
Tbio
Novelty: 0.01443658
Score: 0.766
Data Source: STRINGDB
LILRB2
Tbio
Novelty: 0.00545569
Score: 0.76
Data Source: STRINGDB
Publication Statistics
PubMed Score  291.62

PubMed score by year
PubTator Score  68.15

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer