Protein Summary
May play a role in cell-cell and cell-matrix interactions. May contribute to various neuronal mechanisms in the central nervous system. This gene encodes the protein core of a seminal plasma proteoglycan containing chondroitin- and heparan-sulfate chains. The protein's function is unknown, although similarity to thyropin-type cysteine protease-inhibitors suggests its function may be related to protease inhibition. [provided by RefSeq, Jul 2008]
- ENST00000394945
- ENSP00000378401
- ENSG00000152377
- SPOCK
- TIC1
- TICN1
- TIC1
- SPOCK
- TESTICAN
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
gene perturbation | 0.95 | ||
microRNA | 0.94 | ||
PubMedID | 0.86 | ||
kinase perturbation | 0.84 | ||
transcription factor binding site profile | 0.7 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 117.63 (req: < 5)
Gene RIFs: 43 (req: <= 3)
Antibodies: 119 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 117.63 (req: >= 5)
Gene RIFs: 43 (req: > 3)
Antibodies: 119 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 15
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0