KLC1
Kinesin light chain 1
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
disease perturbation | 1 | ||
transcription factor perturbation | 1 | ||
protein domain | 0.97 | ||
virus perturbation | 0.88 | ||
kinase perturbation | 0.84 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Adaptive Immune System | ||||
Reactome | COPI-dependent Golgi-to-ER retrograde traffic | ||||
Reactome | Factors involved in megakaryocyte development and platelet production | ||||
Reactome | Golgi-to-ER retrograde transport | ||||
Reactome | Hemostasis | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Adaptive Immune System | ||||
COPI-dependent Golgi-to-ER retrograde traffic | ||||
Factors involved in megakaryocyte development and platelet production | ||||
Golgi-to-ER retrograde transport | ||||
Hemostasis | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Traceable Author Statement (TAS) | ProtInc | |||
Inferred from Electronic Annotation (IEA) | InterPro | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
heel bone mineral density | 1 | 3 | 3 | 91.6 | |||||
reticulocyte count | 4 | 3 | 4 | 91.4 | |||||
intelligence | 7 | 9 | 3 | 6 | 82.3 | ||||
10 | 8 | 4 | 1.1 | 80.5 | |||||
serum gamma-glutamyl transferase measurement | 1 | 1 | 1 | 77.3 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
heel bone mineral density | 3 | 91.6 | |||||
reticulocyte count | 4 | 91.4 | |||||
intelligence | 3 | 6 | 82.3 | ||||
4 | 1.1 | 80.5 | |||||
serum gamma-glutamyl transferase measurement | 1 | 77.3 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | kinesin light chain 1 | VGNC:12840 | 453188 | |||||
Macaque | kinesin light chain 1 | 695677 | ||||||
Mouse | MGI:107978 | 16593 | ||||||
Rat | RGD:621411 | 171041 | ||||||
Dog | kinesin light chain 1 | 100855591 | ||||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | kinesin light chain 1 | |||||
Macaque | kinesin light chain 1 | |||||
Mouse | ||||||
Rat | ||||||
Dog | kinesin light chain 1 | |||||
PMID | Text |
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