TJP1
Tight junction protein ZO-1
You are using an outdated browser. Please upgrade your browser to improve your experience.
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
ligand (protein) perturbation | 1 | ||
protein domain | 0.99 | ||
virus perturbation | 0.99 | ||
hub protein | 0.96 | ||
chemical | 0.94 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Apoptosis | ||||
Reactome | Apoptotic cleavage of cell adhesion proteins | ||||
Reactome | Apoptotic cleavage of cellular proteins | ||||
Reactome | Apoptotic execution phase | ||||
Reactome | Gap junction trafficking and regulation | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Apoptosis | ||||
Apoptotic cleavage of cell adhesion proteins | ||||
Apoptotic cleavage of cellular proteins | ||||
Apoptotic execution phase | ||||
Gap junction trafficking and regulation | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from High Throughput Direct Assay (HDA) | BHF-UCL | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
central corneal thickness | 3 | 3 | 0 | 3.9 | 87.6 | ||||
corneal topography | 1 | 1 | 1 | 48.5 | |||||
heel bone mineral density | 1 | 1 | 1 | 38.2 | |||||
body weights and measures | 1 | 1 | 1 | 17.8 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
central corneal thickness | 0 | 3.9 | 87.6 | ||||
corneal topography | 1 | 48.5 | |||||
heel bone mineral density | 1 | 38.2 | |||||
body weights and measures | 1 | 17.8 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | tight junction protein 1 | VGNC:13429 | 453253 | |||||
Mouse | MGI:98759 | 21872 | ||||||
Rat | RGD:1306305 | 292994 | ||||||
Dog | tight junction protein 1 | VGNC:47386 | 403752 | |||||
Horse | tight junction protein 1 | VGNC:24118 | 100050412 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | tight junction protein 1 | |||||
Mouse | ||||||
Rat | ||||||
Dog | tight junction protein 1 | |||||
Horse | tight junction protein 1 | |||||
PMID | Year | Title |
---|