GAD2
Glutamate decarboxylase 2
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
phosphatase | 0.98 | ||
trait | 0.93 | ||
cellular component | 0.92 | ||
disease | 0.85 | ||
molecular function | 0.73 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | GABA synthesis | ||||
Reactome | GABA synthesis, release, reuptake and degradation | ||||
Reactome | Gene expression (Transcription) | ||||
Reactome | Generic Transcription Pathway | ||||
Reactome | MECP2 regulates transcription of genes involved in GABA signaling | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
GABA synthesis | ||||
GABA synthesis, release, reuptake and degradation | ||||
Gene expression (Transcription) | ||||
Generic Transcription Pathway | ||||
MECP2 regulates transcription of genes involved in GABA signaling | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Traceable Author Statement (TAS) | Reactome | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
glucose measurement | 1 | 1 | 1 | 59.6 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
glucose measurement | 1 | 59.6 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | glutamate decarboxylase 2 | VGNC:12337 | 466026 | |||||
Macaque | glutamate decarboxylase 2 | 613029 | ||||||
Mouse | MGI:95634 | 14417 | ||||||
Rat | RGD:2653 | 24380 | ||||||
Dog | glutamate decarboxylase 2 | VGNC:41068 | 487107 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | glutamate decarboxylase 2 | |||||
Macaque | glutamate decarboxylase 2 | |||||
Mouse | ||||||
Rat | ||||||
Dog | glutamate decarboxylase 2 | |||||
PMID | Year | Title |
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