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Tbio
SSBP1
Single-stranded DNA-binding protein, mitochondrial

Protein Summary
Description
This protein binds preferentially and cooperatively to ss-DNA. Probably involved in mitochondrial DNA replication. Associates with mitochondrial DNA. SSBP1 is a housekeeping gene involved in mitochondrial biogenesis (Tiranti et al., 1995 [PubMed 7789991]). It is also a subunit of a single-stranded DNA (ssDNA)-binding complex involved in the maintenance of genome stability (Huang et al., 2009) [PubMed 19683501].[supplied by OMIM, Feb 2010]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000265304
  • ENSP00000265304
  • ENSG00000106028
  • ENST00000465582
  • ENSP00000420485
  • ENST00000481508
  • ENSP00000419665
  • ENST00000484178
  • ENSP00000419388
  • ENST00000498107
  • ENSP00000419541
  • ENST00000570667
  • ENSP00000460028
  • ENSG00000262771
  • ENST00000571430
  • ENSP00000459367
  • ENST00000574199
  • ENSP00000461884
  • ENST00000575059
  • ENSP00000458815
  • ENST00000576834
  • ENSP00000459208
  • ENST00000612337
  • ENSP00000480488

Symbol
  • SSBP
  • SSBP
  • mtSSB
  • Mt-SSB
  • SOSS-B1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
co-expressed gene
1
interacting protein
1
transcription factor binding site profile
0.95
histone modification site profile
0.9
transcription factor perturbation
0.74


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 118.66   (req: < 5)
Gene RIFs: 47   (req: <= 3)
Antibodies: 155   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 118.66   (req: >= 5)
Gene RIFs: 47   (req: > 3)
Antibodies: 155   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 7
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0