KMT2A
Histone-lysine N-methyltransferase 2A
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
gene perturbation | 1 | ||
protein domain | 1 | ||
molecular function | 0.99 | ||
biological process | 0.96 | ||
drug perturbation | 0.87 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Chromatin modifying enzymes | ||||
Reactome | Chromatin organization | ||||
Reactome | Developmental Biology | ||||
Reactome | Gene expression (Transcription) | ||||
Reactome | Generic Transcription Pathway | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Chromatin modifying enzymes | ||||
Chromatin organization | ||||
Developmental Biology | ||||
Gene expression (Transcription) | ||||
Generic Transcription Pathway | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | IntAct | |||
Inferred from Sequence or structural Similarity (ISS) | UniProtKB | |||
Inferred from Sequence Alignment (ISA) | NTNU_SB | |||
Traceable Author Statement (TAS) | Reactome | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
5 | 3 | 0 | 1.4 | 94.9 | |||||
6 | 2 | 0 | 1.3 | 92.2 | |||||
1 | 1 | 0 | 1.1 | 67.4 | |||||
triglyceride measurement | 2 | 1 | 2 | 64.4 | |||||
hematocrit | 2 | 2 | 2 | 64.2 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
0 | 1.4 | 94.9 | |||||
0 | 1.3 | 92.2 | |||||
0 | 1.1 | 67.4 | |||||
triglyceride measurement | 2 | 64.4 | |||||
hematocrit | 2 | 64.2 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | lysine methyltransferase 2A | VGNC:7657 | 451587 | |||||
Macaque | lysine methyltransferase 2A | 705511 | ||||||
Mouse | MGI:96995 | 214162 | ||||||
Rat | RGD:1586165 | 315606 | ||||||
Dog | lysine methyltransferase 2A | VGNC:42489 | 479417 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | lysine methyltransferase 2A | |||||
Macaque | lysine methyltransferase 2A | |||||
Mouse | ||||||
Rat | ||||||
Dog | lysine methyltransferase 2A | |||||
PMID | Year | Title |
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