OCRL
Inositol polyphosphate 5-phosphatase OCRL-1
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
virus perturbation | 0.85 | ||
molecular function | 0.84 | ||
cellular component | 0.79 | ||
microRNA | 0.71 | ||
tissue sample | 0.7 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Clathrin-mediated endocytosis | ||||
Reactome | Golgi Associated Vesicle Biogenesis | ||||
Reactome | Inositol phosphate metabolism | ||||
Reactome | Membrane Trafficking | ||||
Reactome | Metabolism | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Clathrin-mediated endocytosis | ||||
Golgi Associated Vesicle Biogenesis | ||||
Inositol phosphate metabolism | ||||
Membrane Trafficking | ||||
Metabolism | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | FlyBase | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | FlyBase | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Traceable Author Statement (TAS) | Reactome | |||
Traceable Author Statement (TAS) | Reactome | |||
Traceable Author Statement (TAS) | Reactome | |||
Traceable Author Statement (TAS) | Reactome | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
response to darapladib | 1 | 1 | 0 | 4.1 | 3.4 | ||||
Diarrhea | 1 | 1 | 0 | 4.1 | 3.4 | ||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
response to darapladib | 0 | 4.1 | 3.4 | ||||
Diarrhea | 0 | 4.1 | 3.4 | ||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | OCRL, inositol polyphosphate-5-phosphatase | VGNC:10468 | 465851 | |||||
Macaque | OCRL, inositol polyphosphate-5-phosphatase | 702345 | ||||||
Mouse | MGI:109589 | 320634 | ||||||
Rat | RGD:1594526 | 317576 | ||||||
Dog | OCRL, inositol polyphosphate-5-phosphatase | VGNC:44095 | 492123 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | OCRL, inositol polyphosphate-5-phosphatase | |||||
Macaque | OCRL, inositol polyphosphate-5-phosphatase | |||||
Mouse | ||||||
Rat | ||||||
Dog | OCRL, inositol polyphosphate-5-phosphatase | |||||
PMID | Year | Title |
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