Protein Summary
May be a signaling adapter molecule involved in p75NTR-mediated apoptosis induced by NGF. Plays a role in zinc-triggered neuronal death (By similarity). May play an important role in the pathogenesis of neurogenetic diseases.
- ENST00000361298
- ENSP00000354843
- ENSG00000166681
- ENST00000372634
- ENSP00000361717
- ENST00000372635
- ENSP00000361718
- ENST00000372645
- ENSP00000361728
- DXS6984E
- NADE
- NGFRAP1
- Bex
- NADE
- HGR74
- NGFRAP1
- DXS6984E
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
biological process | 0 | ||
biological term | 0 | ||
cell line | 0 | ||
cell type or tissue | 0 | ||
cellular component | 0 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 83.51 (req: < 5)
Gene RIFs: 5 (req: <= 3)
Antibodies: 241 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 83.51 (req: >= 5)
Gene RIFs: 5 (req: > 3)
Antibodies: 241 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 9
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0