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Tbio
PSG4
Pregnancy-specific beta-1-glycoprotein 4

Protein Summary
Description
The protein encoded by this gene is a pregnancy-specific glycoprotein (PSG), one of several encoded by a cluster of similar genes on chromosome 19. This gene is a member of the carcinoembryonic antigen (CEA) gene family and may play a role in regulation of the innate immune system. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000244295
  • ENSP00000244295
  • ENSG00000243137
  • ENST00000405312
  • ENSP00000384770
  • ENST00000433626
  • ENSP00000387864

Symbol
  • CGM4
  • PSG9
  • PSG9
  • PSBG-4
  • PSBG-9
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.85
protein domain
0.73
cell line
0.61
small molecule perturbation
0.56
chemical
0.41


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 12.06   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 80   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 12.06   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 80   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (19)
PSG1
Tbio
Novelty:  0.0239046
p_int:  1
Score:  0.863
Data Source:  BioPlex,STRINGDB
PSG8
Tdark
Novelty:  0.1446257
p_int:  0.999996641
p_ni:  8.3e-8
p_wrong:  0.000003276
Score:  0.621
Data Source:  BioPlex,STRINGDB
GAL3ST1
Tbio
Family:  Enzyme
Novelty:  0.02939055
p_int:  0.994907107
p_ni:  0.005058992
p_wrong:  0.000033901
Score:  0.534
Data Source:  BioPlex,STRINGDB
PSG11
Tbio
Novelty:  0.13331659
p_int:  0.958584828
p_ni:  0.000243196
p_wrong:  0.041171975
Score:  0.701
Data Source:  BioPlex,STRINGDB
SDC2
Tbio
Novelty:  0.00597758
Score:  0.918
Data Source:  STRINGDB
SDC1
Tbio
Novelty:  0.00044792
Score:  0.904
Data Source:  STRINGDB
TGFB1
Tbio
Novelty:  0.0001299
Score:  0.903
Data Source:  STRINGDB
GPC1
Tbio
Novelty:  0.00293087
Score:  0.902
Data Source:  STRINGDB
SDC4
Tbio
Novelty:  0.00319073
Score:  0.902
Data Source:  STRINGDB
SDC3
Tbio
Novelty:  0.01095269
Score:  0.9
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (2)
Cell surface interactions at the vascular wall (R-HSA-202733)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 2 of 2
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Cell surface interactions at the vascular wall
Reactome
Hemostasis
Name
Explore in Pharos
Explore in Source
Cell surface interactions at the vascular wall
Hemostasis
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (2)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-SubCell
Disease Associations ()
No disease associations found
GWAS Traits (0)
No GWAS traits found
IDG Resources
No IDG generated resources found
Orthologs
No orthologs found
Publication Statistics
PubMed Score 12.06
PubMed score by year
PubTator Score 5.41
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title