NFKB2
Nuclear factor NF-kappa-B p100 subunit
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
hub protein | 1 | ||
protein domain | 1 | ||
biological process | 0.93 | ||
virus perturbation | 0.92 | ||
molecular function | 0.91 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | C-type lectin receptors (CLRs) | ||||
Reactome | CLEC7A (Dectin-1) signaling | ||||
Reactome | Chromatin modifying enzymes | ||||
Reactome | Chromatin organization | ||||
Reactome | Cytokine Signaling in Immune system | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
C-type lectin receptors (CLRs) | ||||
CLEC7A (Dectin-1) signaling | ||||
Chromatin modifying enzymes | ||||
Chromatin organization | ||||
Cytokine Signaling in Immune system | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | NTNU_SB | |||
Inferred from Direct Assay (IDA) | NTNU_SB | |||
Inferred from Sequence Alignment (ISA) | NTNU_SB | |||
Traceable Author Statement (TAS) | ProtInc | |||
Traceable Author Statement (TAS) | ProtInc | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
2 | 2 | 0 | 1 | 81.4 | |||||
intelligence | 3 | 4 | 3 | 6.4 | 75.6 | ||||
household income | 1 | 2 | 2 | 67.5 | |||||
cognitive function measurement | 2 | 1 | 2 | 65.6 | |||||
platelet crit | 1 | 1 | 1 | 64.4 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
0 | 1 | 81.4 | |||||
intelligence | 3 | 6.4 | 75.6 | ||||
household income | 2 | 67.5 | |||||
cognitive function measurement | 2 | 65.6 | |||||
platelet crit | 1 | 64.4 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | nuclear factor kappa B subunit 2 | VGNC:10454 | 450697 | |||||
Macaque | nuclear factor kappa B subunit 2 | 714689 | ||||||
Mouse | MGI:1099800 | 18034 | ||||||
Rat | RGD:1307189 | 309452 | ||||||
Dog | nuclear factor kappa B subunit 2 | VGNC:43781 | 486858 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | nuclear factor kappa B subunit 2 | |||||
Macaque | nuclear factor kappa B subunit 2 | |||||
Mouse | ||||||
Rat | ||||||
Dog | nuclear factor kappa B subunit 2 | |||||
PMID | Year | Title |
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