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Tdark
PTPDC1
Protein tyrosine phosphatase domain-containing protein 1

Protein Summary
Description
May play roles in cilia formation and/or maintenance. The protein encoded by this gene contains a characteristic motif of protein tyrosine phosphatases (PTPs). PTPs regulate activities of phosphoproteins through dephosphorylation. They are signaling molecules involved in the regulation of a wide variety of biological processes. The specific function of this protein has not yet been determined. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000288976
  • ENSP00000288976
  • ENSG00000158079
  • ENST00000375360
  • ENSP00000364509
  • ENST00000650567
  • ENSP00000497158

Symbol
  • PTP9Q22
  • PTP9Q22
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.91
tissue sample
0.72
microRNA
0.67
transcription factor
0.61
transcription factor binding site profile
0.59


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.99   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 22   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.99   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 22   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0