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Tbio
PTER
Phosphotriesterase-related protein

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000298942
  • ENSP00000298942
  • ENSG00000165983
  • ENST00000378000
  • ENSP00000367239
  • ENST00000535784
  • ENSP00000439485

Symbol
  • HPHRP
  • RPR-1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.85
transcription factor perturbation
0.8
cell type or tissue
0.68
disease perturbation
0.68
virus perturbation
0.68


Protein Classes
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 80.96   (req: < 5)
Gene RIFs: 5   (req: <= 3)
Antibodies: 95   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 80.96   (req: >= 5)
Gene RIFs: 5   (req: > 3)
Antibodies: 95   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (84)
NPDC1
Tbio
Novelty:  0.05766647
p_int:  0.999890493
p_ni:  0.000109483
p_wrong:  2.4e-8
Score:  0.243
Data Source:  BioPlex,STRINGDB
TEKT2
Tbio
Novelty:  0.04607893
p_int:  0.999859451
p_ni:  0.000140541
p_wrong:  8e-9
Score:  0.189
Data Source:  BioPlex,STRINGDB
CDKN2D
Tbio
Family:  Enzyme
Novelty:  0.01445471
p_int:  0.999633438
p_ni:  0.000366548
p_wrong:  1.4e-8
Data Source:  BioPlex
KHDRBS2
Tbio
Novelty:  0.01986638
p_int:  0.998034605
p_ni:  0.001962663
p_wrong:  0.000002732
Score:  0.18
Data Source:  BioPlex,STRINGDB
CARTPT
Tbio
Novelty:  0.00224864
p_int:  0.996266828
p_ni:  0.003677004
p_wrong:  0.000056168
Data Source:  BioPlex
SNX3
Tbio
Novelty:  0.02703152
p_int:  0.99624948
p_ni:  0.002316472
p_wrong:  0.001434048
Data Source:  BioPlex
HYAL3
Tbio
Family:  Enzyme
Novelty:  0.14284007
p_int:  0.994960389
p_ni:  0.002319703
p_wrong:  0.002719909
Score:  0.252
Data Source:  BioPlex,STRINGDB
TMEM51
Tdark
Novelty:  0.54147214
p_int:  0.99433841
p_ni:  0.005656611
p_wrong:  0.000004979
Score:  0.169
Data Source:  BioPlex,STRINGDB
LIPH
Tbio
Family:  Enzyme
Novelty:  0.00961658
p_int:  0.992618037
p_ni:  0.00264845
p_wrong:  0.004733514
Score:  0.185
Data Source:  BioPlex,STRINGDB
DNAJB3
Tdark
p_int:  0.992540492
p_ni:  0.007415297
p_wrong:  0.000044211
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
metabolite measurement
1
1
1
80.4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
metabolite measurement
1
80.4
IDG Resources
No IDG generated resources found
Orthologs (15)
1 – 5 of 15
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
phosphotriesterase related
VGNC:5710
450325
Macaque
phosphotriesterase related
699387
Mouse
MGI:107372
19212
Rat
RGD:61313
63852
Dog
phosphotriesterase related
VGNC:45139
477994
Species
Name
OMA
EggNOG
Inparanoid
Chimp
phosphotriesterase related
Macaque
phosphotriesterase related
Mouse
Rat
Dog
phosphotriesterase related
Publication Statistics
PubMed Score 80.96
PubMed score by year
PubTator Score 22.79
PubTator score by year
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Related Publications
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PMID
Year
Title