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Tbio
PTCHD3
Patched domain-containing protein 3

Protein Summary
Description
May play a role in sperm development or sperm function.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000438700
  • ENSP00000417658
  • ENSG00000182077
  • ENST00000617711
  • ENSP00000484143
  • ENSG00000276595

Symbol
  • PTR
  • PTR
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.64
cell line
0.47
protein complex
0.4
phenotype
0.39
disease
0.38


Protein Classes
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 319.63   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 109   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 319.63   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 109   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (3)
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (64)
ADCK2
Tbio
Family:  Kinase
Novelty:  0.13237052
p_int:  0.999953872
p_ni:  0.000046127
p_wrong:  1e-9
Data Source:  BioPlex
BTN2A2
Tbio
Novelty:  0.46565474
p_int:  0.996806809
p_ni:  0.003193184
p_wrong:  7e-9
Data Source:  BioPlex
ST7L
Tbio
Novelty:  0.03661324
p_int:  0.995872068
p_ni:  0.003978418
p_wrong:  0.000149514
Data Source:  BioPlex
TAP2
Tbio
Novelty:  0.0390555
p_int:  0.993343047
p_ni:  0.006480205
p_wrong:  0.000176749
Data Source:  BioPlex
SARAF
Tbio
Novelty:  0.0383833
p_int:  0.993275437
p_ni:  0.006722061
p_wrong:  0.000002501
Data Source:  BioPlex
HMGCR
Tclin
Family:  Enzyme
Novelty:  0.00046789
p_int:  0.992128034
p_ni:  0.007871966
Data Source:  BioPlex
ABCD4
Tbio
Family:  Transporter
Novelty:  0.04096359
p_int:  0.990466385
p_ni:  0.009533511
p_wrong:  1.03e-7
Data Source:  BioPlex
DNAJC18
Tdark
Novelty:  1.38573997
p_int:  0.984841861
p_ni:  0.015157999
p_wrong:  1.4e-7
Data Source:  BioPlex
CYP51A1
Tchem
Family:  Enzyme
Novelty:  0.00127373
p_int:  0.984177737
p_ni:  0.015822263
Data Source:  BioPlex
FADS1
Tchem
Family:  Enzyme
Novelty:  0.00160193
p_int:  0.97655402
p_ni:  0.022674111
p_wrong:  0.000771869
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (0)
No GWAS traits found
IDG Resources
No IDG generated resources found
Orthologs (10)
1 – 5 of 10
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
patched domain containing 3
VGNC:51989
450371
Macaque
patched domain containing 3
715111
Mouse
MGI:1921925
74675
Rat
RGD:1590039
688333
Horse
patched domain containing 3
VGNC:21982
100065129
Species
Name
OMA
EggNOG
Inparanoid
Chimp
patched domain containing 3
Macaque
patched domain containing 3
Mouse
Rat
Horse
patched domain containing 3
Publication Statistics
PubMed Score 319.63
PubMed score by year
PubTator Score 15.21
PubTator score by year
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Related Publications
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PMID
Year
Title