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Tdark
PTCD2
Pentatricopeptide repeat-containing protein 2, mitochondrial

Protein Summary
Description
Involved in mitochondrial RNA maturation and mitochondrial respiratory chain function.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000308077
  • ENSP00000308948
  • ENSG00000049883
  • ENST00000380639
  • ENSP00000370013
  • ENST00000503868
  • ENSP00000427349
  • ENST00000536805
  • ENSP00000444772
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
disease perturbation
0.95
histone modification site profile
0.89
kinase perturbation
0.84
transcription factor binding site profile
0.71
tissue sample
0.58


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.3   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 176   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.3   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 176   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 8
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0