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Tchem
PSMG3
Proteasome assembly chaperone 3

Protein Summary
Description
Chaperone protein which promotes assembly of the 20S proteasome. May cooperate with PSMG1-PSMG2 heterodimers to orchestrate the correct assembly of proteasomes.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000252329
  • ENSP00000252329
  • ENSG00000157778
  • ENST00000288607
  • ENSP00000288607
  • ENST00000404674
  • ENSP00000384799

Symbol
  • C7orf48
  • PAC3
  • PAC3
  • C7orf48
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.81
transcription factor binding site profile
0.78
kinase perturbation
0.66
tissue sample
0.64
transcription factor
0.64


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 75.09   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 59   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 75.09   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 59   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligands: 2
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0