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Tdark
PSG8
Pregnancy-specific beta-1-glycoprotein 8

Protein Summary
Description
The human pregnancy-specific glycoproteins (PSGs) are a group of molecules that are mainly produced by the placental syncytiotrophoblasts during pregnancy. PSGs comprise a subgroup of the carcinoembryonic antigen (CEA) family, which belongs to the immunoglobulin superfamily. For additional general information about the PSG gene family, see PSG1 (MIM 176390).[supplied by OMIM, Oct 2009]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000306511
  • ENSP00000305005
  • ENSG00000124467
  • ENST00000404209
  • ENSP00000385869
  • ENST00000406636
  • ENSP00000385081

Symbol
  • PSG1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein domain
0.73
microRNA
0.59
cell line
0.55
tissue sample
0.36
disease
0.34


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.57   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 10   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.57   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 10   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (43)
PSG1
Tbio
Novelty:  0.0239046
p_int:  0.999999998
p_ni:  1e-9
p_wrong:  2e-9
Score:  0.75
Data Source:  BioPlex,STRINGDB
CELSR3
Tbio
Family:  GPCR
Novelty:  0.02705624
p_int:  0.999996916
p_ni:  0.00000306
p_wrong:  2.4e-8
Data Source:  BioPlex
PSG4
Tbio
Novelty:  0.09464871
p_int:  0.999996641
p_ni:  8.3e-8
p_wrong:  0.000003276
Score:  0.621
Data Source:  BioPlex,STRINGDB
MCM9
Tbio
Family:  Enzyme
Novelty:  0.0390791
p_int:  0.999979088
p_ni:  0.00002091
p_wrong:  2e-9
Score:  0.2
Data Source:  BioPlex,STRINGDB
PEX7
Tbio
Novelty:  0.01487923
p_int:  0.99997416
p_ni:  0.000025836
p_wrong:  4e-9
Data Source:  BioPlex
TUBB1
Tclin
Novelty:  0.02806117
p_int:  0.999900664
p_ni:  0.000099335
p_wrong:  1e-9
Data Source:  BioPlex
GFM2
Tbio
Novelty:  0.02945848
p_int:  0.999887262
p_ni:  0.000112736
p_wrong:  2e-9
Data Source:  BioPlex
CBWD3
Tdark
Novelty:  0.03639787
p_int:  0.999606563
p_ni:  0.000393405
p_wrong:  3.2e-8
Data Source:  BioPlex
ACOT9
Tbio
Family:  Enzyme
Novelty:  0.17405187
p_int:  0.999383687
p_ni:  0.000616313
Data Source:  BioPlex
RHOBTB1
Tbio
Novelty:  0.02152609
p_int:  0.999011775
p_ni:  0.000161671
p_wrong:  0.000826554
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (2)
Cell surface interactions at the vascular wall (R-HSA-202733)

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Find Similar Targets
Items per page:
1 – 2 of 2
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Cell surface interactions at the vascular wall
Reactome
Hemostasis
Name
Explore in Pharos
Explore in Source
Cell surface interactions at the vascular wall
Hemostasis
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
birth weight
1
1
1
31.4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
birth weight
1
31.4
IDG Resources
No IDG generated resources found
Orthologs
No orthologs found
Publication Statistics
PubMed Score 6.57
PubMed score by year
PubTator Score 1.09
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title