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Tbio
PRSS50
Probable threonine protease PRSS50

Protein Summary
Description
May be involved in proteolysis through its threonine endopeptidase activity.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000460241
  • ENSP00000418875
  • ENSG00000206549

Symbol
  • CT20
  • TSP50
  • CT20
  • TSP50
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
gene perturbation
0.77
cell type or tissue
0.76
tissue sample
0.49
cell line
0.47
phenotype
0.45


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 71.48   (req: < 5)
Gene RIFs: 17   (req: <= 3)
Antibodies: 117   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 71.48   (req: >= 5)
Gene RIFs: 17   (req: > 3)
Antibodies: 117   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (3)
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (57)
PRSS46P
Tdark
Family:  Enzyme
Novelty:  1.2979351
p_int:  1
Score:  0.531
Data Source:  BioPlex,STRINGDB
CBWD3
Tdark
Novelty:  0.03639787
p_int:  0.999881476
p_ni:  0.00011848
p_wrong:  4.4e-8
Data Source:  BioPlex
TUBB1
Tclin
Novelty:  0.02806117
p_int:  0.999391477
p_ni:  0.00060849
p_wrong:  3.3e-8
Data Source:  BioPlex
ZYG11B
Tbio
Novelty:  0.14657862
p_int:  0.973155429
p_ni:  0.026844571
Data Source:  BioPlex
FKBP14
Tbio
Family:  Enzyme
Novelty:  0.02742616
p_int:  0.954868829
p_ni:  0.033493456
p_wrong:  0.011637715
Data Source:  BioPlex
ADAMTS1
Tchem
Family:  Enzyme
Novelty:  0.00483758
p_int:  0.924269308
p_ni:  0.075730692
Score:  0.189
Data Source:  BioPlex,STRINGDB
PIGS
Tdark
Family:  Enzyme
Novelty:  0.36443235
p_int:  0.887081043
p_ni:  0.112918957
Score:  0.606
Data Source:  BioPlex,STRINGDB
USP54
Tdark
Family:  Enzyme
Novelty:  0.31344498
p_int:  0.869009951
p_ni:  0.127248706
p_wrong:  0.003741343
Data Source:  BioPlex
HSPA5
Tchem
Novelty:  0.00043424
p_int:  0.866725982
p_ni:  0.133274018
Score:  0.178
Data Source:  BioPlex,STRINGDB
GPAA1
Tbio
Novelty:  0.01874575
p_int:  0.854583587
p_ni:  0.145416413
Score:  0.527
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (0)
No GWAS traits found
IDG Resources
No IDG generated resources found
Orthologs (5)
1 – 5 of 5
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Mouse
MGI:2447303
235631
Rat
RGD:6499372
100910205
Dog
protease, serine 50
476646
Horse
protease, serine 50
100065064
Opossum
protease, serine 50
103101447
Species
Name
OMA
EggNOG
Inparanoid
Mouse
Rat
Dog
protease, serine 50
Horse
protease, serine 50
Opossum
protease, serine 50
Publication Statistics
PubMed Score 71.48
PubMed score by year
PubTator Score 37.15
PubTator score by year
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Related Publications
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PMID
Year
Title