PRSS23
Serine protease 23
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
transcription factor perturbation | 1 | ||
PubMedID | 0.99 | ||
small molecule perturbation | 0.73 | ||
kinase perturbation | 0.71 | ||
disease perturbation | 0.68 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Metabolism of proteins | ||||
Reactome | Post-translational protein modification | ||||
Reactome | Post-translational protein phosphorylation | ||||
Reactome | Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Metabolism of proteins | ||||
Post-translational protein modification | ||||
Post-translational protein phosphorylation | ||||
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Electronic Annotation (IEA) | InterPro | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
heel bone mineral density | 3 | 2 | 4 | 93.7 | |||||
intraocular pressure measurement | 3 | 4 | 5 | 81.5 | |||||
blood urea nitrogen measurement | 1 | 1 | 1 | 56.6 | |||||
cup-to-disc ratio measurement | 2 | 2 | 2 | 54.3 | |||||
serum urea measurement | 1 | 1 | 1 | 36.9 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
heel bone mineral density | 4 | 93.7 | |||||
intraocular pressure measurement | 5 | 81.5 | |||||
blood urea nitrogen measurement | 1 | 56.6 | |||||
cup-to-disc ratio measurement | 2 | 54.3 | |||||
serum urea measurement | 1 | 36.9 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Macaque | protease, serine 23 | 704537 | ||||||
Mouse | MGI:1923703 | 76453 | ||||||
Rat | RGD:1359545 | 308807 | ||||||
Dog | serine protease 23 | VGNC:45065 | 485150 | |||||
Horse | serine protease 23 | VGNC:21914 | 100060937 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Macaque | protease, serine 23 | |||||
Mouse | ||||||
Rat | ||||||
Dog | serine protease 23 | |||||
Horse | serine protease 23 | |||||
PMID | Year | Title |
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