PRSS23
Serine protease 23
Protein Summary
This gene encodes a conserved member of the trypsin family of serine proteases. Mouse studies found a decrease of mRNA levels of this gene after ovulation was induced. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]
- ENST00000280258
- ENSP00000280258
- ENSG00000150687
- ZSIG13
- SIG13
- SPUVE
- ZSIG13
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
transcription factor perturbation | 1 | ||
PubMedID | 0.99 | ||
small molecule perturbation | 0.73 | ||
kinase perturbation | 0.71 | ||
disease perturbation | 0.68 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 15.2 (req: < 5)
Gene RIFs: 5 (req: <= 3)
Antibodies: 68 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 15.2 (req: >= 5)
Gene RIFs: 5 (req: > 3)
Antibodies: 68 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 3
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0