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Tdark
PRRT3
Proline-rich transmembrane protein 3

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000295984
  • ENSP00000295984
  • ENSG00000163704
  • ENST00000411976
  • ENSP00000404512
  • ENST00000412055
  • ENSP00000392511
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.64
PubMedID
0.56
tissue sample
0.55
cell type or tissue
0.5
tissue
0.46


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.45   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 28   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.45   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 28   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (37)
PTPRD
Tbio
Family:  Enzyme
Novelty:  0.01059407
p_int:  0.887204664
p_ni:  0.112793265
p_wrong:  0.000002071
Data Source:  BioPlex
YWHAE
Tbio
Novelty:  0.00431876
p_int:  0.791363604
p_ni:  0.208636396
Data Source:  BioPlex
METTL27
Tdark
Novelty:  0.34658724
Score:  0.703
Data Source:  STRINGDB
NTSR2
Tchem
Family:  GPCR
Novelty:  0.00699381
Score:  0.674
Data Source:  STRINGDB
FANCD2OS
Tdark
Novelty:  9.51798561
Score:  0.668
Data Source:  STRINGDB
ATP13A5
Tdark
Family:  Transporter
Novelty:  0.46360279
Score:  0.605
Data Source:  STRINGDB
ATP13A4
Tdark
Family:  Transporter
Novelty:  0.15634665
Score:  0.605
Data Source:  STRINGDB
ATP13A3
Tbio
Family:  Transporter
Novelty:  0.13498113
Score:  0.605
Data Source:  STRINGDB
ATP13A2
Tbio
Family:  Transporter
Novelty:  0.00623191
Score:  0.605
Data Source:  STRINGDB
TATDN2
Tdark
Family:  Enzyme
Novelty:  1.40236433
Score:  0.576
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (2)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
body height
1
1
1
40.6
body mass index
1
1
1
31.4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
body height
1
40.6
body mass index
1
31.4
IDG Resources
No IDG generated resources found
Orthologs (6)
1 – 5 of 6
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
proline rich transmembrane protein 3
VGNC:7106
460161
Macaque
proline rich transmembrane protein 3
699097
Mouse
MGI:2444810
210673
Rat
RGD:1562419
502873
Dog
proline rich transmembrane protein 3
VGNC:45059
484660
Species
Name
OMA
EggNOG
Inparanoid
Chimp
proline rich transmembrane protein 3
Macaque
proline rich transmembrane protein 3
Mouse
Rat
Dog
proline rich transmembrane protein 3
Publication Statistics
PubMed Score 3.45
PubMed score by year
PubTator Score 1.83
PubTator score by year
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Related Publications
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PMID
Year
Title