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Tbio
PRRC2A
Protein PRRC2A

Protein Summary
Description
May play a role in the regulation of pre-mRNA splicing. A cluster of genes, BAT1-BAT5, has been localized in the vicinity of the genes for TNF alpha and TNF beta. These genes are all within the human major histocompatibility complex class III region. This gene has microsatellite repeats which are associated with the age-at-onset of insulin-dependent diabetes mellitus (IDDM) and possibly thought to be involved with the inflammatory process of pancreatic beta-cell destruction during the development of IDDM. This gene is also a candidate gene for the development of rheumatoid arthritis. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Dec 2010]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000376007
  • ENSP00000365175
  • ENSG00000204469
  • ENST00000376033
  • ENSP00000365201
  • ENST00000383455
  • ENSP00000372947
  • ENSG00000206427
  • ENST00000383464
  • ENSP00000372956
  • ENST00000414956
  • ENSP00000404619
  • ENSG00000226618
  • ENST00000416335
  • ENSP00000415182
  • ENSG00000231370
  • ENST00000422962
  • ENSP00000415363
  • ENSG00000231825
  • ENST00000428775
  • ENSP00000387910
  • ENSG00000225164
  • ENST00000430737
  • ENSP00000413977
  • ENST00000432252
  • ENSP00000408226
  • ENSG00000225748
  • ENST00000435971
  • ENSP00000409444
  • ENST00000439762
  • ENSP00000400540
  • ENST00000454306
  • ENSP00000387477
  • ENST00000458561
  • ENSP00000396812

Symbol
  • BAT2
  • G2
  • G2
  • BAT2
  • D6S51
  • D6S51E
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
drug perturbation
1
interacting protein
0.88
hub protein
0.85
disease
0.84
phenotype
0.82


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 114.49   (req: < 5)
Gene RIFs: 14   (req: <= 3)
Antibodies: 10   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 114.49   (req: >= 5)
Gene RIFs: 14   (req: > 3)
Antibodies: 10   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0