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Tdark
PRR3
Proline-rich protein 3

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000376557
  • ENSP00000365740
  • ENSG00000204576
  • ENST00000376560
  • ENSP00000365744
  • ENST00000383592
  • ENSP00000373086
  • ENSG00000206491
  • ENST00000418065
  • ENSP00000404669
  • ENST00000422140
  • ENSP00000411802
  • ENSG00000228186
  • ENST00000422639
  • ENSP00000401499
  • ENSG00000229202
  • ENST00000427729
  • ENSP00000402596
  • ENSG00000223766
  • ENST00000432371
  • ENSP00000396416
  • ENST00000436805
  • ENSP00000406321
  • ENSG00000233564
  • ENST00000442290
  • ENSP00000401612
  • ENSG00000223887
  • ENST00000444972
  • ENSP00000393410
  • ENST00000449754
  • ENSP00000398352
  • ENST00000453232
  • ENSP00000415432
  • ENST00000454399
  • ENSP00000392826

Symbol
  • CAT56
  • CAT56
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cellular component
0.75
transcription factor
0.74
microRNA
0.71
small molecule perturbation
0.64
cell type or tissue
0.62


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.56   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 28   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.56   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 28   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (30)
RPS2
Tbio
Novelty:  0.00412313
p_int:  0.985173913
p_ni:  0.000505946
p_wrong:  0.014320141
Data Source:  BioPlex
NOP53
Tbio
Novelty:  0.00353077
p_int:  0.977599758
p_ni:  0.018371227
p_wrong:  0.004029014
Data Source:  BioPlex
FGF8
Tbio
Novelty:  0.00155113
p_int:  0.934491192
p_ni:  0.002931942
p_wrong:  0.062576867
Data Source:  BioPlex
NIFK
Tbio
Novelty:  0.01221562
p_int:  0.848142403
p_ni:  0.141683631
p_wrong:  0.010173965
Data Source:  BioPlex
RBMX
Tbio
Novelty:  0.01705784
Score:  0.806
Data Source:  STRINGDB
HNRNPK
Tbio
Novelty:  0.00354731
Score:  0.748
Data Source:  STRINGDB
TRIM10
Tbio
Novelty:  0.27685659
Score:  0.706
Data Source:  STRINGDB
APOBEC3C
Tbio
Novelty:  0.00882074
Score:  0.69
Data Source:  STRINGDB
PPP1R11
Tbio
Family:  Enzyme
Novelty:  0.08166535
Score:  0.684
Data Source:  STRINGDB
KHDRBS3
Tbio
Novelty:  0.00490069
Score:  0.641
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (2)
Find Similar Targets
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from High Throughput Direct Assay (HDA)
UniProtKB
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Disease Associations (null)
No disease associations found
GWAS Traits (108)
Items per page:
1 – 5 of 108
GWAS Trait
EFO ID
ENSG ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
platelet crit
1
1
1
76
platelet crit
1
1
1
76
platelet crit
1
1
1
76
platelet crit
1
1
1
76
platelet crit
1
1
1
76
Items per page:
1 – 5 of 108
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
platelet crit
1
76
platelet crit
1
76
platelet crit
1
76
platelet crit
1
76
platelet crit
1
76
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (6)
1 – 5 of 6
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
proline rich 3
VGNC:11189
462542
Macaque
proline rich 3
711699
Mouse
MGI:1922460
75210
Rat
RGD:1303270
361788
Cow
proline rich 3
VGNC:33396
525344
Species
Name
OMA
EggNOG
Inparanoid
Chimp
proline rich 3
Macaque
proline rich 3
Mouse
Rat
Cow
proline rich 3
Publication Statistics
PubMed Score 0.56
PubMed score by year
PubTator Score 2.77
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title