PRPF31
U4/U6 small nuclear ribonucleoprotein Prp31
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
disease perturbation | 0.97 | ||
interacting protein | 0.97 | ||
histone modification site profile | 0.91 | ||
co-expressed gene | 0.87 | ||
transcription factor binding site profile | 0.85 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Metabolism of RNA | ||||
Reactome | Processing of Capped Intron-Containing Pre-mRNA | ||||
Reactome | mRNA Splicing | ||||
Reactome | mRNA Splicing - Major Pathway | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Metabolism of RNA | ||||
Processing of Capped Intron-Containing Pre-mRNA | ||||
mRNA Splicing | ||||
mRNA Splicing - Major Pathway | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | MGI | |||
Inferred from Direct Assay (IDA) | GO_Central | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | BHF-UCL | |||
Inferred from High Throughput Direct Assay (HDA) | UniProtKB | |||
GWAS Trait | EFO ID | ENSG ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|---|
alkaline phosphatase measurement | 2 | 3 | 3 | 18.1 | 97.7 | |||||
alkaline phosphatase measurement | 2 | 3 | 3 | 18.1 | 97.7 | |||||
blood metabolite measurement | 2 | 2 | 2 | 89.9 | ||||||
blood metabolite measurement | 2 | 2 | 2 | 89.9 | ||||||
phosphatidylinositol measurement | 1 | 1 | 3 | 78.4 | ||||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
alkaline phosphatase measurement | 3 | 18.1 | 97.7 | ||||
alkaline phosphatase measurement | 3 | 18.1 | 97.7 | ||||
blood metabolite measurement | 2 | 89.9 | |||||
blood metabolite measurement | 2 | 89.9 | |||||
phosphatidylinositol measurement | 3 | 78.4 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | pre-mRNA processing factor 31 | VGNC:12068 | 107969799 | |||||
Macaque | pre-mRNA processing factor 31 | 720567 | ||||||
Mouse | MGI:1916238 | 68988 | ||||||
Rat | RGD:1305832 | 292536 | ||||||
Dog | pre-mRNA processing factor 31 | VGNC:45021 | 476389 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | pre-mRNA processing factor 31 | |||||
Macaque | pre-mRNA processing factor 31 | |||||
Mouse | ||||||
Rat | ||||||
Dog | pre-mRNA processing factor 31 | |||||
PMID | Year | Title |
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