PRKCZ
Protein kinase C zeta type
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
biological process | 1 | ||
hub protein | 1 | ||
protein domain | 1 | ||
molecular function | 0.99 | ||
biological term | 0.98 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | ESR-mediated signaling | ||||
Reactome | Estrogen-stimulated signaling through PRKCZ | ||||
Reactome | Extra-nuclear estrogen signaling | ||||
Reactome | GPVI-mediated activation cascade | ||||
Reactome | Hemostasis | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
ESR-mediated signaling | ||||
Estrogen-stimulated signaling through PRKCZ | ||||
Extra-nuclear estrogen signaling | ||||
GPVI-mediated activation cascade | ||||
Hemostasis | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | BHF-UCL | |||
Traceable Author Statement (TAS) | Reactome | |||
Inferred by Curator (IC) | BHF-UCL | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
platelet count | 2 | 2 | 2 | 83.7 | |||||
platelet crit | 2 | 2 | 2 | 80.4 | |||||
serum alanine aminotransferase measurement | 2 | 2 | 1 | 6 | 76.2 | ||||
electrocardiography | 1 | 1 | 88 | 68.6 | |||||
low density lipoprotein cholesterol measurement | 1 | 1 | 1 | 52.4 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
platelet count | 2 | 83.7 | |||||
platelet crit | 2 | 80.4 | |||||
serum alanine aminotransferase measurement | 1 | 6 | 76.2 | ||||
electrocardiography | 88 | 68.6 | |||||
low density lipoprotein cholesterol measurement | 1 | 52.4 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Macaque | protein kinase C zeta type-like | 100430236 | ||||||
Mouse | MGI:97602 | 18762 | ||||||
Rat | RGD:3399 | 25522 | ||||||
Dog | protein kinase C zeta | VGNC:44985 | 479577 | |||||
Horse | protein kinase C zeta | VGNC:21850 | 100064240 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Macaque | protein kinase C zeta type-like | |||||
Mouse | ||||||
Rat | ||||||
Dog | protein kinase C zeta | |||||
Horse | protein kinase C zeta | |||||
PMID | Year | Title |
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