PRKCI
Protein kinase C iota type
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
protein domain | 1 | ||
biological process | 0.99 | ||
interacting protein | 0.99 | ||
molecular function | 0.97 | ||
virus perturbation | 0.94 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Cell junction organization | ||||
Reactome | Cell-Cell communication | ||||
Reactome | Cell-cell junction organization | ||||
Reactome | Death Receptor Signalling | ||||
Reactome | Pre-NOTCH Expression and Processing | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Cell junction organization | ||||
Cell-Cell communication | ||||
Cell-cell junction organization | ||||
Death Receptor Signalling | ||||
Pre-NOTCH Expression and Processing | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Sequence or structural Similarity (ISS) | BHF-UCL | |||
Traceable Author Statement (TAS) | UniProtKB | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
4 | 2 | 0 | 1.2 | 76.9 | |||||
glomerular filtration rate | 3 | 2 | 3 | 31.3 | |||||
creatinine measurement | 2 | 1 | 2 | 17.8 | |||||
urinary albumin to creatinine ratio | 3 | 1 | 3 | 14.1 | |||||
albuminuria | 1 | 1 | 1 | 12.6 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
0 | 1.2 | 76.9 | |||||
glomerular filtration rate | 3 | 31.3 | |||||
creatinine measurement | 2 | 17.8 | |||||
urinary albumin to creatinine ratio | 3 | 14.1 | |||||
albuminuria | 1 | 12.6 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | protein kinase C iota | VGNC:12133 | 450143 | |||||
Mouse | MGI:99260 | 18759 | ||||||
Rat | RGD:620961 | 84006 | ||||||
Dog | protein kinase C iota | VGNC:44982 | 478686 | |||||
Horse | protein kinase C iota | VGNC:21847 | 100063737 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | protein kinase C iota | |||||
Mouse | ||||||
Rat | ||||||
Dog | protein kinase C iota | |||||
Horse | protein kinase C iota | |||||
PMID | Year | Title |
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