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Tdark
PRELID2
PRELI domain-containing protein 2

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000334744
  • ENSP00000335675
  • ENSG00000186314
  • ENST00000394450
  • ENSP00000377965
  • ENST00000505416
  • ENSP00000424730
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.85
kinase perturbation
0.76
microRNA
0.67
tissue sample
0.65
transcription factor perturbation
0.61


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.68   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 61   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.68   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 61   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (41)
EXPH5
Tbio
Novelty:  0.07504682
p_int:  0.999942622
p_ni:  0.000046737
p_wrong:  0.000010641
Data Source:  BioPlex
NCOA4
Tbio
Novelty:  0.00487453
p_int:  0.999404899
p_ni:  0.000204141
p_wrong:  0.00039096
Data Source:  BioPlex
BUB1
Tchem
Family:  Kinase
Novelty:  0.00327514
p_int:  0.998917312
p_ni:  0.001058822
p_wrong:  0.000023866
Data Source:  BioPlex
ALMS1
Tbio
Novelty:  0.00694228
p_int:  0.998084015
p_ni:  0.001915985
Data Source:  BioPlex
KNL1
Tbio
Novelty:  0.01084826
p_int:  0.991866133
p_ni:  0.008133867
Data Source:  BioPlex
FAM83D
Tbio
Novelty:  0.07381559
p_int:  0.962555717
p_ni:  0.037431005
p_wrong:  0.000013278
Data Source:  BioPlex
KIF11
Tchem
Novelty:  0.00170673
p_int:  0.950040287
p_ni:  0.049959713
Data Source:  BioPlex
MLF1
Tbio
Novelty:  0.0239522
p_int:  0.941317898
p_ni:  0.058682035
p_wrong:  6.7e-8
Data Source:  BioPlex
TP73
Tbio
Family:  TF
Novelty:  0.00667737
p_int:  0.930118207
p_ni:  0.069881793
Data Source:  BioPlex
CDK5RAP2
Tbio
Novelty:  0.00956263
p_int:  0.922178716
p_ni:  0.077820425
p_wrong:  8.58e-7
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (2)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
smoking status measurement
1
1
1
17.8
vitamin B12 measurement
1
1
0
43.9
15.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
smoking status measurement
1
17.8
vitamin B12 measurement
0
43.9
15.8
IDG Resources
No IDG generated resources found
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
PRELI domain containing 2
VGNC:4136
739950
Macaque
PRELI domain containing 2
706848
Mouse
MGI:1924869
77619
Rat
RGD:1584707
681037
Dog
PRELI domain containing 2
VGNC:44956
607778
Species
Name
OMA
EggNOG
Inparanoid
Chimp
PRELI domain containing 2
Macaque
PRELI domain containing 2
Mouse
Rat
Dog
PRELI domain containing 2
Publication Statistics
PubMed Score 2.68
PubMed score by year
PubTator Score 0.20
PubTator score by year
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Related Publications
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PMID
Year
Title