You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
PPWD1
Peptidylprolyl isomerase domain and WD repeat-containing protein 1

Protein Summary
Description
PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding (PubMed:20676357). May be involved in pre-mRNA splicing (PubMed:11991638).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000261308
  • ENSP00000261308
  • ENSG00000113593
  • ENST00000538977
  • ENSP00000444496

Symbol
  • KIAA0073
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.91
tissue sample
0.75
protein domain
0.73
disease perturbation
0.62
cell type or tissue
0.58


Protein Classes
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.65   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 186   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.65   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 186   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0