PPRC1
Peroxisome proliferator-activated receptor gamma coactivator-related protein 1
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
kinase perturbation | 1 | ||
transcription factor binding site profile | 0.96 | ||
disease perturbation | 0.74 | ||
cell type or tissue | 0.68 | ||
molecular function | 0.67 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Mitochondrial biogenesis | ||||
Reactome | Organelle biogenesis and maintenance | ||||
Reactome | Transcriptional activation of mitochondrial biogenesis | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Mitochondrial biogenesis | ||||
Organelle biogenesis and maintenance | ||||
Transcriptional activation of mitochondrial biogenesis | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from High Throughput Direct Assay (HDA) | UniProtKB | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
self reported educational attainment | 4 | 3 | 6 | 6.6 | 92.7 | ||||
cognitive function measurement | 2 | 3 | 3 | 90.7 | |||||
intelligence | 4 | 8 | 7 | 6.2 | 90.1 | ||||
mean reticulocyte volume | 1 | 2 | 2 | 81.6 | |||||
mean corpuscular volume | 1 | 1 | 1 | 77.9 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
self reported educational attainment | 6 | 6.6 | 92.7 | ||||
cognitive function measurement | 3 | 90.7 | |||||
intelligence | 7 | 6.2 | 90.1 | ||||
mean reticulocyte volume | 2 | 81.6 | |||||
mean corpuscular volume | 1 | 77.9 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | peroxisome proliferator-activated receptor gamma, coactivator-related 1 | 450696 | ||||||
Macaque | peroxisome proliferator-activated receptor gamma, coactivator-related 1 | 712721 | ||||||
Mouse | MGI:2385096 | 226169 | ||||||
Rat | RGD:1309688 | 294007 | ||||||
Dog | peroxisome proliferator-activated receptor gamma, coactivator-related 1 | VGNC:44928 | 477805 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | peroxisome proliferator-activated receptor gamma, coactivator-related 1 | |||||
Macaque | peroxisome proliferator-activated receptor gamma, coactivator-related 1 | |||||
Mouse | ||||||
Rat | ||||||
Dog | peroxisome proliferator-activated receptor gamma, coactivator-related 1 | |||||
PMID | Year | Title |
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