You are using an outdated browser. Please upgrade your browser to improve your experience.

Tdark
PPIAL4G
Peptidyl-prolyl cis-trans isomerase A-like 4G

Protein Summary
Description
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000419275
  • ENSP00000393845
  • ENSG00000236334

Symbol
  • COAS-2
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
tissue sample
0.71
protein domain
0.58
microRNA
0.42
tissue
0.39
cell line
0.27


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.86   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 71   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.86   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 71   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (3)
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (35)
PPIAL4D
Tdark
Family:  Enzyme
Novelty:  56
p_int:  1
Data Source:  BioPlex
PPIAL4A
Tdark
Family:  Enzyme
Novelty:  0.76101999
p_int:  1
Data Source:  BioPlex
FAT3
Tbio
Novelty:  0.03661008
p_int:  0.999793993
p_ni:  0.000206007
Score:  0.158
Data Source:  BioPlex,STRINGDB
DCHS1
Tbio
Novelty:  0.02220058
p_int:  0.998616322
p_ni:  0.001383634
p_wrong:  4.4e-8
Score:  0.235
Data Source:  BioPlex,STRINGDB
FAT4
Tbio
Novelty:  0.01739918
p_int:  0.997318652
p_ni:  0.002681348
Data Source:  BioPlex
VPS13A
Tbio
Novelty:  0.00581335
p_int:  0.992461765
p_ni:  0.007538235
Score:  0.189
Data Source:  BioPlex,STRINGDB
PCDHGA11
Tdark
Novelty:  0.44130091
p_int:  0.971698825
p_ni:  0.007021097
p_wrong:  0.021280078
Score:  0.534
Data Source:  BioPlex,STRINGDB
ACTBL2
Tbio
Novelty:  0.18080702
p_int:  0.953423875
p_ni:  0.046576125
Score:  0.169
Data Source:  BioPlex,STRINGDB
ACTB
Tbio
Novelty:  0.00006048
p_int:  0.928796179
p_ni:  0.071203821
Score:  0.191
Data Source:  BioPlex,STRINGDB
INTS14
Tdark
Novelty:  1.33783374
p_int:  0.906325512
p_ni:  0.089227602
p_wrong:  0.004446886
Score:  0.169
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (0)
No GWAS traits found
IDG Resources
No IDG generated resources found
Orthologs
No orthologs found
Publication Statistics
PubMed Score 0.86
PubMed score by year
loading...
Related Publications
Items per page:
0 of 0
PMID
Year
Title