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Tdark
PPIAL4A
Peptidyl-prolyl cis-trans isomerase A-like 4A

Protein Summary
Description
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000577856
  • ENSP00000485206
  • ENSG00000263353

Symbol
  • COAS2
  • PPIAL4B
  • COAS2
  • COAS-2
  • PPIAL4
  • PPIAL4B
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.93
tissue
0.59
protein domain
0.58
cell line
0.57
protein complex
0.4


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.9   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 35   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.9   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 35   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (3)
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (11)
PPIAL4G
Tdark
Family:  Enzyme
Novelty:  0.93726521
p_int:  1
Data Source:  BioPlex
NBPF12
Tdark
Novelty:  0.01235433
Score:  0.8
Data Source:  STRINGDB
PPP3CA
Tchem
Family:  Enzyme
Novelty:  0.00234189
Score:  0.742
Data Source:  STRINGDB
PRSS38
Tdark
Family:  Enzyme
Novelty:  0.19685291
Score:  0.515
Data Source:  STRINGDB
PPP3CC
Tbio
Family:  Enzyme
Novelty:  0.02633046
Score:  0.482
Data Source:  STRINGDB
PPP3CB
Tbio
Family:  Enzyme
Novelty:  0.02156713
Score:  0.482
Data Source:  STRINGDB
SNU13
Tbio
Novelty:  0.01613497
Score:  0.434
Data Source:  STRINGDB
EEF2
Tchem
Novelty:  0.00064095
Score:  0.429
Data Source:  STRINGDB
WDR92
Tbio
Novelty:  55
Score:  0.427
Data Source:  STRINGDB
BUD31
Tbio
Novelty:  0.13364384
Score:  0.414
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (0)
No GWAS traits found
IDG Resources
No IDG generated resources found
Orthologs
No orthologs found
Publication Statistics
PubMed Score 0.90
PubMed score by year
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Related Publications
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PMID
Year
Title