POLR3E
DNA-directed RNA polymerase III subunit RPC5
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
transcription factor binding site profile | 0.97 | ||
kinase perturbation | 0.91 | ||
interacting protein | 0.89 | ||
transcription factor perturbation | 0.8 | ||
histone modification site profile | 0.75 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Cytosolic sensors of pathogen-associated DNA | ||||
Reactome | Gene expression (Transcription) | ||||
Reactome | Immune System | ||||
Reactome | Innate Immune System | ||||
Reactome | RNA Polymerase III Abortive And Retractive Initiation | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Cytosolic sensors of pathogen-associated DNA | ||||
Gene expression (Transcription) | ||||
Immune System | ||||
Innate Immune System | ||||
RNA Polymerase III Abortive And Retractive Initiation | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | ENSG ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|---|
heel bone mineral density | 2 | 2 | 2 | 71.1 | ||||||
heel bone mineral density | 2 | 2 | 2 | 71.1 | ||||||
body height | 1 | 1 | 1 | 42.3 | ||||||
body height | 1 | 1 | 1 | 42.3 | ||||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
heel bone mineral density | 2 | 71.1 | |||||
heel bone mineral density | 2 | 71.1 | |||||
body height | 1 | 42.3 | |||||
body height | 1 | 42.3 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | RNA polymerase III subunit E | VGNC:8994 | 454351 | |||||
Macaque | RNA polymerase III subunit E | 697901 | ||||||
Mouse | MGI:1349452 | 26939 | ||||||
Rat | RGD:1308086 | 361640 | ||||||
Dog | RNA polymerase III subunit E | VGNC:54059 | 608689 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | RNA polymerase III subunit E | |||||
Macaque | RNA polymerase III subunit E | |||||
Mouse | ||||||
Rat | ||||||
Dog | RNA polymerase III subunit E | |||||
PMID | Year | Title |
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