POLR2D
DNA-directed RNA polymerase II subunit RPB4
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
biological process | 0.95 | ||
disease perturbation | 0.9 | ||
kinase perturbation | 0.88 | ||
transcription factor perturbation | 0.84 | ||
histone modification site profile | 0.81 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Abortive elongation of HIV-1 transcript in the absence of Tat | ||||
Reactome | Activation of HOX genes during differentiation | ||||
Reactome | Activation of anterior HOX genes in hindbrain development during early embryogenesis | ||||
Reactome | DNA Repair | ||||
Reactome | Developmental Biology | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Abortive elongation of HIV-1 transcript in the absence of Tat | ||||
Activation of HOX genes during differentiation | ||||
Activation of anterior HOX genes in hindbrain development during early embryogenesis | ||||
DNA Repair | ||||
Developmental Biology | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Mutant Phenotype (IMP) | UniProtKB | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Electronic Annotation (IEA) | InterPro | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
leukocyte count | 1 | 1 | 1 | 33.1 | |||||
high density lipoprotein cholesterol measurement | 1 | 1 | 1 | 11.8 | |||||
apolipoprotein A 1 measurement | 1 | 1 | 1 | 10 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
leukocyte count | 1 | 33.1 | |||||
high density lipoprotein cholesterol measurement | 1 | 11.8 | |||||
apolipoprotein A 1 measurement | 1 | 10 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | RNA polymerase II subunit D | VGNC:8361 | 100612569 | |||||
Macaque | RNA polymerase II subunit D | 699945 | ||||||
Mouse | MGI:1916491 | 69241 | ||||||
Rat | RGD:1308565 | 364834 | ||||||
Dog | RNA polymerase II subunit D | VGNC:44795 | 483863 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | RNA polymerase II subunit D | |||||
Macaque | RNA polymerase II subunit D | |||||
Mouse | ||||||
Rat | ||||||
Dog | RNA polymerase II subunit D | |||||
PMID | Year | Title |
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