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Tdark
POGK
Pogo transposable element with KRAB domain

Protein Summary
Description
The exact function of the protein encoded by this gene is not known. However, this gene product contains a KRAB domain (which is involved in protein-protein interactions) at the N-terminus, and a transposase domain at the C-terminus, suggesting that it may belong to the family of DNA-mediated transposons in human. [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000367875
  • ENSP00000356849
  • ENSG00000143157
  • ENST00000367876
  • ENSP00000356850

Symbol
  • KIAA1513
  • BASS2
  • KRBOX2
  • LST003
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor perturbation
0.96
virus perturbation
0.9
kinase perturbation
0.81
microRNA
0.76
protein domain
0.73


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.78   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 304   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.78   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 304   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (46)
TRIM28
Tbio
Family:  Epigenetic
Novelty:  0.00778381
p_int:  0.999999959
p_ni:  3.9e-8
p_wrong:  2e-9
Data Source:  BioPlex
TCEAL1
Tbio
Novelty:  0.02210924
p_int:  0.999985902
p_ni:  0.000003481
p_wrong:  0.000010617
Score:  0.173
Data Source:  BioPlex,STRINGDB
ARPC1B
Tbio
Novelty:  0.03873325
p_int:  0.999973642
p_ni:  0.000026346
p_wrong:  1.2e-8
Score:  0.234
Data Source:  BioPlex,STRINGDB
ARL2BP
Tbio
Novelty:  0.03460574
p_int:  0.999911936
p_ni:  0.000058213
p_wrong:  0.000029851
Data Source:  BioPlex
TRIM11
Tbio
Family:  Enzyme
Novelty:  0.02243955
p_int:  0.999841122
p_ni:  0.000158878
Data Source:  BioPlex
CCNDBP1
Tbio
Novelty:  0.01527762
p_int:  0.999674722
p_ni:  0.000325274
p_wrong:  4e-9
Score:  0.201
Data Source:  BioPlex,STRINGDB
EVI5L
Tbio
Novelty:  0.70769557
Score:  0.766
Data Source:  STRINGDB
MITD1
Tbio
Novelty:  0.30899265
Score:  0.747
Data Source:  STRINGDB
ZBED8
Tdark
Novelty:  2.26997341
Score:  0.719
Data Source:  STRINGDB
PGBD2
Tdark
Novelty:  2.01193283
Score:  0.709
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (4)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Disease Associations (null)
No disease associations found
GWAS Traits (5)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
neutrophil count
3
2
3
74.5
myeloid white cell count
1
1
1
57.7
leukocyte count
3
3
3
53.2
neutrophil percentage of leukocytes
1
1
1
25.8
sex hormone-binding globulin measurement
1
1
1
7.2
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
neutrophil count
3
74.5
myeloid white cell count
1
57.7
leukocyte count
3
53.2
neutrophil percentage of leukocytes
1
25.8
sex hormone-binding globulin measurement
1
7.2
IDG Resources
No IDG generated resources found
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
pogo transposable element derived with KRAB domain
VGNC:1463
747301
Macaque
pogo transposable element derived with KRAB domain
696834
Mouse
MGI:1918842
71592
Rat
RGD:1308951
304941
Dog
pogo transposable element derived with KRAB domain
VGNC:44768
100855429
Species
Name
OMA
EggNOG
Inparanoid
Chimp
pogo transposable element derived with KRAB domain
Macaque
pogo transposable element derived with KRAB domain
Mouse
Rat
Dog
pogo transposable element derived with KRAB domain
Publication Statistics
PubMed Score 3.78
PubMed score by year
PubTator Score 1.00
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title