PNPO
Pyridoxine-5'-phosphate oxidase
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
kinase perturbation | 0.88 | ||
transcription factor perturbation | 0.84 | ||
histone modification site profile | 0.8 | ||
disease perturbation | 0.79 | ||
virus perturbation | 0.79 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Metabolism | ||||
Reactome | Metabolism of vitamins and cofactors | ||||
Reactome | Metabolism of water-soluble vitamins and cofactors | ||||
Reactome | Vitamins B6 activation to pyridoxal phosphate | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Metabolism | ||||
Metabolism of vitamins and cofactors | ||||
Metabolism of water-soluble vitamins and cofactors | ||||
Vitamins B6 activation to pyridoxal phosphate | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | CAFA | |||
Inferred from Direct Assay (IDA) | CAFA | |||
Inferred from Direct Assay (IDA) | CAFA | |||
Inferred from Direct Assay (IDA) | CAFA | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
hair color | 2 | 3 | 0 | 1.1 | 93.5 | ||||
BMI-adjusted hip circumference | 2 | 4 | 5 | 77.3 | |||||
hematocrit | 1 | 1 | 1 | 63.4 | |||||
neutrophil count | 2 | 2 | 2 | 46.9 | |||||
1 | 1 | 1 | 40.7 | ||||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
hair color | 0 | 1.1 | 93.5 | ||||
BMI-adjusted hip circumference | 5 | 77.3 | |||||
hematocrit | 1 | 63.4 | |||||
neutrophil count | 2 | 46.9 | |||||
1 | 40.7 | ||||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | pyridoxamine 5'-phosphate oxidase | VGNC:9532 | 749248 | |||||
Macaque | pyridoxamine 5'-phosphate oxidase | 694949 | ||||||
Mouse | MGI:2144151 | 103711 | ||||||
Rat | RGD:621456 | 64533 | ||||||
Dog | pyridoxamine 5'-phosphate oxidase | VGNC:44759 | 480540 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | pyridoxamine 5'-phosphate oxidase | |||||
Macaque | pyridoxamine 5'-phosphate oxidase | |||||
Mouse | ||||||
Rat | ||||||
Dog | pyridoxamine 5'-phosphate oxidase | |||||
PMID | Year | Title |
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