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Tdark
PNMA8A
Paraneoplastic antigen-like protein 8A

Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.97   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 50   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.97   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 50   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (46)
RARG
Tclin
Family:  NR
Novelty:  0.00667159
p_int:  0.999999924
p_ni:  6.1e-8
p_wrong:  1.6e-8
Score:  0.269
Data Source:  BioPlex,STRINGDB
PNMA1
Tbio
Novelty:  0.06899807
p_int:  0.999997546
p_ni:  0.000002427
p_wrong:  2.6e-8
Score:  0.847
Data Source:  BioPlex,STRINGDB
MOAP1
Tbio
Novelty:  0.05070263
p_int:  0.999993487
p_ni:  0.000006421
p_wrong:  9.2e-8
Score:  0.863
Data Source:  BioPlex,STRINGDB
CES2
Tchem
Family:  Enzyme
Novelty:  0.00177726
p_int:  0.998756423
p_ni:  0.001243566
p_wrong:  1.1e-8
Data Source:  BioPlex
POLE3
Tbio
Family:  Enzyme
Novelty:  0.09657513
p_int:  0.997753729
p_ni:  0.002246234
p_wrong:  3.6e-8
Data Source:  BioPlex
RTL9
Tbio
Novelty:  0.15059774
Score:  0.769
Data Source:  STRINGDB
RTL5
Tdark
Novelty:  0.07868053
Score:  0.73
Data Source:  STRINGDB
RTL3
Tdark
Novelty:  0.27058386
Score:  0.712
Data Source:  STRINGDB
RTL6
Tbio
Novelty:  0.12824182
Score:  0.703
Data Source:  STRINGDB
ZCCHC12
Tbio
Novelty:  0.16283891
Score:  0.687
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (0)
No GO Terms found
Disease Associations ()
No disease associations found
GWAS Traits (8)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
Oral ulcer
1
2
0
1.1
88
triglyceride measurement
1
1
1
59.6
reticulocyte count
1
1
1
55.2
hemoglobin measurement
2
1
2
53.3
eosinophil count
1
1
1
44.2
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
Oral ulcer
0
1.1
88
triglyceride measurement
1
59.6
reticulocyte count
1
55.2
hemoglobin measurement
2
53.3
eosinophil count
1
44.2
IDG Resources
No IDG generated resources found
Orthologs (8)
1 – 5 of 8
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
PNMA family member 8A
VGNC:48989
468928
Macaque
PNMA family member 8A
716385
Mouse
MGI:1918941
71691
Rat
RGD:1310803
361515
Dog
PNMA family member 8A [Source:HGNC Symbol;Acc:HGNC:25578]
Species
Name
OMA
EggNOG
Inparanoid
Chimp
PNMA family member 8A
Macaque
PNMA family member 8A
Mouse
Rat
Dog
PNMA family member 8A [Source:HGNC Symbol;Acc:HGNC:25578]
Publication Statistics
PubMed Score 0.97
PubMed score by year
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Related Publications
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PMID
Year
Title