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Tdark
PNMA5
Paraneoplastic antigen-like protein 5

Protein Summary
Description
This gene encodes a member of the paraneoplastic Ma antigen protein family. These proteins have been implicated in the development of paraneoplastic disorders resulting from an immune response directed against them. Paraneoplastic disorders are the result of an abnormal immune response to a tumor. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Oct 2011]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000361887
  • ENSP00000354834
  • ENSG00000198883
  • ENST00000439251
  • ENSP00000388850
  • ENST00000452693
  • ENSP00000392342
  • ENST00000535214
  • ENSP00000445775

Symbol
  • KIAA1934
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.98
cellular component
0.64
PubMedID
0.46
protein complex
0.4
transcription factor
0.39


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.12   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 101   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.12   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 101   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (3)
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (24)
ZBTB8A
Tdark
Family:  TF
Novelty:  0.65458116
p_int:  0.999997886
p_ni:  1.07e-7
p_wrong:  0.000002007
Score:  0.54
Data Source:  BioPlex,STRINGDB
UACA
Tbio
Novelty:  0.05853699
p_int:  0.999943983
p_ni:  0.000055976
p_wrong:  4e-8
Score:  0.228
Data Source:  BioPlex,STRINGDB
GTF3C2
Tdark
Novelty:  0.1827844
p_int:  0.97380806
p_ni:  0.02619194
Score:  0.19
Data Source:  BioPlex,STRINGDB
CARNMT1
Tbio
Family:  Enzyme
Novelty:  0.28121779
p_int:  0.827670689
p_ni:  0.172329289
p_wrong:  2.2e-8
Score:  0.173
Data Source:  BioPlex,STRINGDB
RTL3
Tdark
Novelty:  0.27058386
Score:  0.818
Data Source:  STRINGDB
ZNF251
Tdark
Family:  TF
Novelty:  0.74149728
Score:  0.777
Data Source:  STRINGDB
PEG10
Tbio
Novelty:  0.00478545
Score:  0.658
Data Source:  STRINGDB
LDOC1
Tbio
Novelty:  0.04366903
Score:  0.6
Data Source:  STRINGDB
ZNF426
Tdark
Family:  TF
Novelty:  0.19450662
Score:  0.583
Data Source:  STRINGDB
ZIK1
Tdark
Family:  TF
Novelty:  0.20771106
Score:  0.569
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (0)
No GWAS traits found
IDG Resources
No IDG generated resources found
Orthologs (4)
1 – 4 of 4
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
PNMA family member 5
693718
Mouse
MGI:2180566
385377
Rat
RGD:1565857
309266
Horse
PNMA family member 5
VGNC:21627
100146340
Species
Name
OMA
EggNOG
Inparanoid
Macaque
PNMA family member 5
Mouse
Rat
Horse
PNMA family member 5
Publication Statistics
PubMed Score 3.12
PubMed score by year
PubTator Score 0.79
PubTator score by year
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Related Publications
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PMID
Year
Title