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Tdark
PM20D2
Peptidase M20 domain-containing protein 2

IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.81   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 102   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.81   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 102   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (38)
GPSM3
Tbio
Novelty:  0.01632501
p_int:  0.99984709
p_ni:  0.00015291
Data Source:  BioPlex
HAO2
Tchem
Family:  Enzyme
Novelty:  0.03029536
p_int:  0.999430132
p_ni:  0.000569868
Score:  0.175
Data Source:  BioPlex,STRINGDB
DEFB1
Tbio
Novelty:  0.00144458
p_int:  0.995213617
p_ni:  0.004786383
Score:  0.228
Data Source:  BioPlex,STRINGDB
ANGPTL4
Tbio
Novelty:  0.00237867
p_int:  0.991501179
p_ni:  0.008498821
Score:  0.228
Data Source:  BioPlex,STRINGDB
KIAA1671
Tdark
Novelty:  1.1816849
p_int:  0.947669009
p_ni:  0.05233089
p_wrong:  1.01e-7
Score:  0.188
Data Source:  BioPlex,STRINGDB
SPATA2
Tbio
Novelty:  0.10553772
p_int:  0.932552552
p_ni:  0.067447448
Data Source:  BioPlex
LNP1
Tdark
Novelty:  0.00457285
p_int:  0.909373844
p_ni:  0.090626156
Data Source:  BioPlex
PRIM2
Tbio
Family:  Enzyme
Novelty:  0.05145449
p_int:  0.879065905
p_ni:  0.120789866
p_wrong:  0.00014423
Score:  0.239
Data Source:  BioPlex,STRINGDB
TK1
Tchem
Family:  Kinase
Novelty:  0.00139343
p_int:  0.802131713
p_ni:  0.197868286
p_wrong:  1e-9
Score:  0.326
Data Source:  BioPlex,STRINGDB
SRSF12
Tbio
Novelty:  0.34992606
Score:  0.752
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (8)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
lifestyle measurement
1
1
1
39.6
blood metabolite measurement
1
1
1
21
monocyte percentage of leukocytes
1
1
1
13.1
monocyte count
1
1
1
12.1
sleep duration
1
1
1
4.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
lifestyle measurement
1
39.6
blood metabolite measurement
1
21
monocyte percentage of leukocytes
1
13.1
monocyte count
1
12.1
sleep duration
1
4.8
IDG Resources
No IDG generated resources found
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
peptidase M20 domain containing 2
VGNC:3625
462882
Macaque
peptidase M20 domain containing 2
700609
Mouse
MGI:2685270
242377
Rat
RGD:1307853
313130
Dog
peptidase M20 domain containing 2
VGNC:44728
100856633
Species
Name
OMA
EggNOG
Inparanoid
Chimp
peptidase M20 domain containing 2
Macaque
peptidase M20 domain containing 2
Mouse
Rat
Dog
peptidase M20 domain containing 2
Publication Statistics
PubMed Score 1.81
PubMed score by year
PubTator Score 0.50
PubTator score by year
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Related Publications
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PMID
Year
Title