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Tdark
PLSCR5
Phospholipid scramblase family member 5

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000443512
  • ENSP00000390111
  • ENSG00000231213
  • ENST00000482567
  • ENSP00000418626
  • ENST00000492200
  • ENSP00000417184
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
metabolite
0.98
tissue
0.49
cell line
0.46
protein domain
0.26
phenotype
0.24


Protein Classes
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.57   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 26   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.57   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 26   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (23)
ANO6
Tbio
Family:  IC
Novelty:  0.01288434
Score:  0.781
Data Source:  STRINGDB
ANO3
Tbio
Novelty:  0.02326536
Score:  0.693
Data Source:  STRINGDB
XKR8
Tbio
Novelty:  0.08472323
Score:  0.692
Data Source:  STRINGDB
ANO2
Tchem
Family:  IC
Novelty:  0.01239394
Score:  0.684
Data Source:  STRINGDB
ANO9
Tbio
Novelty:  0.16467408
Score:  0.664
Data Source:  STRINGDB
ANO10
Tbio
Novelty:  0.03373977
Score:  0.65
Data Source:  STRINGDB
ANO1
Tclin
Family:  IC
Novelty:  0.00143722
Score:  0.623
Data Source:  STRINGDB
MUC20
Tbio
Novelty:  0.04645313
Score:  0.622
Data Source:  STRINGDB
MUC4
Tbio
Novelty:  0.00193208
Score:  0.622
Data Source:  STRINGDB
ANO4
Tbio
Novelty:  0.10053632
Score:  0.6
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (9)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
COVID-19
1
1
0
1.2
33.5
antisocial behaviour measurement
1
1
1
10.1
1
1
1
10.1
substance abuse
1
1
1
10.1
gut microbiome measurement
1
1
1
7.9
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
COVID-19
0
1.2
33.5
antisocial behaviour measurement
1
10.1
1
10.1
substance abuse
1
10.1
gut microbiome measurement
1
7.9
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (10)
1 – 5 of 10
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
phospholipid scramblase family member 5
VGNC:7096
460758
Mouse
MGI:3779462
100504689
Rat
RGD:1564500
501036
Dog
phospholipid scramblase family member 5
VGNC:52896
611511
Horse
phospholipid scramblase family member 5
VGNC:52419
100050969
Species
Name
OMA
EggNOG
Inparanoid
Chimp
phospholipid scramblase family member 5
Mouse
Rat
Dog
phospholipid scramblase family member 5
Horse
phospholipid scramblase family member 5
Publication Statistics
PubMed Score 0.57
PubMed score by year
PubTator Score 0.11
PubTator score by year
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Related Publications
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PMID
Year
Title