PLRG1
Pleiotropic regulator 1
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
interacting protein | 1 | ||
disease perturbation | 0.83 | ||
histone modification site profile | 0.82 | ||
kinase perturbation | 0.81 | ||
transcription factor binding site profile | 0.79 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Metabolism of RNA | ||||
Reactome | Processing of Capped Intron-Containing Pre-mRNA | ||||
Reactome | mRNA Splicing | ||||
Reactome | mRNA Splicing - Major Pathway | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Metabolism of RNA | ||||
Processing of Capped Intron-Containing Pre-mRNA | ||||
mRNA Splicing | ||||
mRNA Splicing - Major Pathway | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | HPA | |||
Inferred from Direct Assay (IDA) | HPA | |||
Inferred from Direct Assay (IDA) | HPA | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Traceable Author Statement (TAS) | Reactome | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
fibrinogen measurement | 8 | 14 | 14 | 12.9 | 99.8 | ||||
7 | 5 | 2 | 1.2 | 98.2 | |||||
low density lipoprotein cholesterol measurement | 3 | 3 | 3 | 89.2 | |||||
prothrombin time measurement | 1 | 1 | 1 | 72.9 | |||||
total cholesterol measurement | 3 | 2 | 3 | 70.5 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
fibrinogen measurement | 14 | 12.9 | 99.8 | ||||
2 | 1.2 | 98.2 | |||||
low density lipoprotein cholesterol measurement | 3 | 89.2 | |||||
prothrombin time measurement | 1 | 72.9 | |||||
total cholesterol measurement | 3 | 70.5 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | pleiotropic regulator 1 | VGNC:669 | 461557 | |||||
Macaque | pleiotropic regulator 1 | 701044 | ||||||
Mouse | MGI:1858197 | 53317 | ||||||
Rat | RGD:621047 | 60376 | ||||||
Dog | pleiotropic regulator 1 | VGNC:44710 | 612490 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | pleiotropic regulator 1 | |||||
Macaque | pleiotropic regulator 1 | |||||
Mouse | ||||||
Rat | ||||||
Dog | pleiotropic regulator 1 | |||||
PMID | Year | Title |
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