PKN3
Serine/threonine-protein kinase N3
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
protein domain | 0.99 | ||
molecular function | 0.93 | ||
histone modification site profile | 0.74 | ||
transcription factor | 0.68 | ||
tissue sample | 0.57 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | RHO GTPase Effectors | ||||
Reactome | RHO GTPases activate PKNs | ||||
Reactome | Signal Transduction | ||||
Reactome | Signaling by Rho GTPases | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
RHO GTPase Effectors | ||||
RHO GTPases activate PKNs | ||||
Signal Transduction | ||||
Signaling by Rho GTPases | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Traceable Author Statement (TAS) | ProtInc | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
Inferred from Electronic Annotation (IEA) | InterPro | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-EC | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
serum gamma-glutamyl transferase measurement | 2 | 2 | 2 | 91.9 | |||||
platelet crit | 2 | 2 | 2 | 89.4 | |||||
sex hormone-binding globulin measurement | 6 | 1 | 6 | 83.3 | |||||
platelet count | 1 | 1 | 1 | 71.6 | |||||
myeloid white cell count | 1 | 1 | 1 | 70.2 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
serum gamma-glutamyl transferase measurement | 2 | 91.9 | |||||
platelet crit | 2 | 89.4 | |||||
sex hormone-binding globulin measurement | 6 | 83.3 | |||||
platelet count | 1 | 71.6 | |||||
myeloid white cell count | 1 | 70.2 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | protein kinase N3 | VGNC:4822 | 464773 | |||||
Macaque | protein kinase N3 | 717319 | ||||||
Mouse | MGI:2388285 | 263803 | ||||||
Dog | protein kinase N3 | VGNC:44613 | 491313 | |||||
Horse | protein kinase N3 | VGNC:21499 | 100066882 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | protein kinase N3 | |||||
Macaque | protein kinase N3 | |||||
Mouse | ||||||
Dog | protein kinase N3 | |||||
Horse | protein kinase N3 | |||||
PMID | Year | Title |
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