PITHD1
PITH domain-containing protein 1
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
histone modification site profile | 0.91 | ||
kinase perturbation | 0.81 | ||
transcription factor perturbation | 0.8 | ||
transcription factor binding site profile | 0.68 | ||
disease perturbation | 0.62 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from High Throughput Direct Assay (HDA) | UniProtKB | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
reticulocyte count | 6 | 4 | 6 | 92.4 | |||||
eosinophil count | 3 | 3 | 3 | 91.9 | |||||
reticulocyte measurement | 3 | 2 | 3 | 90.5 | |||||
eosinophil percentage of leukocytes | 2 | 2 | 2 | 85.5 | |||||
eosinophil percentage of granulocytes | 1 | 1 | 1 | 35 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
reticulocyte count | 6 | 92.4 | |||||
eosinophil count | 3 | 91.9 | |||||
reticulocyte measurement | 3 | 90.5 | |||||
eosinophil percentage of leukocytes | 2 | 85.5 | |||||
eosinophil percentage of granulocytes | 1 | 35 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | PITH domain containing 1 | VGNC:10031 | 456621 | |||||
Macaque | PITH domain containing 1 | 710737 | ||||||
Mouse | MGI:1913443 | 66193 | ||||||
Rat | RGD:1308048 | 298557 | ||||||
Dog | PITH domain containing 1 | VGNC:44582 | 612304 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | PITH domain containing 1 | |||||
Macaque | PITH domain containing 1 | |||||
Mouse | ||||||
Rat | ||||||
Dog | PITH domain containing 1 | |||||
PMID | Year | Title |
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