PIP4K2C
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
disease perturbation | 0.95 | ||
molecular function | 0.93 | ||
kinase perturbation | 0.88 | ||
histone modification site profile | 0.74 | ||
interacting protein | 0.74 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Gene expression (Transcription) | ||||
Reactome | Generic Transcription Pathway | ||||
Reactome | Intracellular signaling by second messengers | ||||
Reactome | Metabolism | ||||
Reactome | Metabolism of lipids | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Gene expression (Transcription) | ||||
Generic Transcription Pathway | ||||
Intracellular signaling by second messengers | ||||
Metabolism | ||||
Metabolism of lipids | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Experiment (EXP) | Reactome | |||
Inferred from Physical Interaction (IPI) | IntAct | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
urate measurement | 1 | 2 | 2 | 80.9 | |||||
1 | 1 | 0 | 1.4 | 56.4 | |||||
body fat distribution | 1 | 1 | 2 | 31.4 | |||||
IGF-1 measurement | 1 | 1 | 1 | 30.2 | |||||
systolic blood pressure | 1 | 1 | 1 | 29.9 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
urate measurement | 2 | 80.9 | |||||
0 | 1.4 | 56.4 | |||||
body fat distribution | 2 | 31.4 | |||||
IGF-1 measurement | 1 | 30.2 | |||||
systolic blood pressure | 1 | 29.9 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | phosphatidylinositol-5-phosphate 4-kinase type 2 gamma | VGNC:13339 | 467044 | |||||
Mouse | MGI:2152214 | 117150 | ||||||
Rat | RGD:621711 | 140607 | ||||||
Dog | phosphatidylinositol-5-phosphate 4-kinase type 2 gamma | VGNC:44572 | 474417 | |||||
Horse | phosphatidylinositol-5-phosphate 4-kinase type 2 gamma | VGNC:21464 | 100053518 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | phosphatidylinositol-5-phosphate 4-kinase type 2 gamma | |||||
Mouse | ||||||
Rat | ||||||
Dog | phosphatidylinositol-5-phosphate 4-kinase type 2 gamma | |||||
Horse | phosphatidylinositol-5-phosphate 4-kinase type 2 gamma | |||||
PMID | Year | Title |
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