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Tdark
PINLYP
phospholipase A2 inhibitor and Ly6/PLAUR domain-containing protein

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000562255
  • ENSP00000457623
  • ENSG00000234465
  • ENST00000562365
  • ENSP00000456310
  • ENST00000569031
  • ENSP00000457369
  • ENST00000599207
  • ENSP00000469886
  • ENST00000612042
  • ENSP00000479240
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.88
tissue sample
0.69
cell line
0.6
transcription factor
0.48
protein domain
0.41


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.69   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 4   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.69   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 4   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (29)
LY6L
Tdark
Novelty:  14.46115589
Score:  0.673
Data Source:  STRINGDB
PATE3
Tdark
Novelty:  0.64960844
Score:  0.668
Data Source:  STRINGDB
PATE2
Tdark
Novelty:  0.33130253
Score:  0.587
Data Source:  STRINGDB
LYPD8
Tdark
Novelty:  0.15320165
Score:  0.581
Data Source:  STRINGDB
BTK
Tclin
Family:  Kinase
Novelty:  0.00050747
Score:  0.58
Data Source:  STRINGDB
LYPD5
Tdark
Novelty:  0.97576337
Score:  0.562
Data Source:  STRINGDB
PATE4
Tdark
Novelty:  0.36651579
Score:  0.56
Data Source:  STRINGDB
LY6G5B
Tdark
Novelty:  0.07346971
Score:  0.538
Data Source:  STRINGDB
SPACA4
Tdark
Novelty:  0.21569953
Score:  0.535
Data Source:  STRINGDB
LYPD4
Tbio
Novelty:  0.00381728
Score:  0.532
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (29)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
urokinase plasminogen activator surface receptor measurement
2
4
4
99.2
TNF-related apoptosis-inducing ligand measurement
2
1
2
89.9
neutrophil count
4
1
4
78.3
myeloid white cell count
2
1
2
78.2
leukocyte count
3
1
3
77.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
urokinase plasminogen activator surface receptor measurement
4
99.2
TNF-related apoptosis-inducing ligand measurement
2
89.9
neutrophil count
4
78.3
myeloid white cell count
2
78.2
leukocyte count
3
77.8
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (7)
1 – 5 of 7
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Mouse
MGI:3615324
641361
Rat
RGD:1565787
308429
Dog
phospholipase A2 inhibitor and LY6/PLAUR domain containing
VGNC:44568
484468
Horse
phospholipase A2 inhibitor and LY6/PLAUR domain containing
VGNC:21459
100070215
Cow
phospholipase A2 inhibitor and Ly6/PLAUR domain-containing protein
616860
Species
Name
OMA
EggNOG
Inparanoid
Mouse
Rat
Dog
phospholipase A2 inhibitor and LY6/PLAUR domain containing
Horse
phospholipase A2 inhibitor and LY6/PLAUR domain containing
Cow
phospholipase A2 inhibitor and Ly6/PLAUR domain-containing protein
Publication Statistics
PubMed Score 0.69
PubMed score by year
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Related Publications
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0 of 0
PMID
Year
Title