PIM1
Serine/threonine-protein kinase pim-1
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
disease perturbation | 1 | ||
PubMedID | 1 | ||
molecular function | 0.98 | ||
virus perturbation | 0.98 | ||
transcription factor binding site profile | 0.96 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Cytokine Signaling in Immune system | ||||
Reactome | Immune System | ||||
Reactome | Interleukin-4 and Interleukin-13 signaling | ||||
Reactome | Signaling by Interleukins | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Cytokine Signaling in Immune system | ||||
Immune System | ||||
Interleukin-4 and Interleukin-13 signaling | ||||
Signaling by Interleukins | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | UniProtKB | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
mean corpuscular volume | 1 | 1 | 1 | 75.5 | |||||
mean reticulocyte volume | 1 | 2 | 2 | 69.2 | |||||
red blood cell distribution width | 2 | 1 | 2 | 60.5 | |||||
platelet count | 1 | 1 | 1 | 24.3 | |||||
monocyte percentage of leukocytes | 1 | 1 | 1 | 12.8 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
mean corpuscular volume | 1 | 75.5 | |||||
mean reticulocyte volume | 2 | 69.2 | |||||
red blood cell distribution width | 2 | 60.5 | |||||
platelet count | 1 | 24.3 | |||||
monocyte percentage of leukocytes | 1 | 12.8 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Mouse | MGI:97584 | 18712 | ||||||
Rat | RGD:3330 | 24649 | ||||||
Horse | Pim-1 proto-oncogene, serine/threonine kinase | VGNC:21456 | 100053898 | |||||
Cow | Pim-1 proto-oncogene, serine/threonine kinase | VGNC:32899 | 281402 | |||||
Pig | Pim-1 proto-oncogene, serine/threonine kinase | 100157844 | ||||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Mouse | ||||||
Rat | ||||||
Horse | Pim-1 proto-oncogene, serine/threonine kinase | |||||
Cow | Pim-1 proto-oncogene, serine/threonine kinase | |||||
Pig | Pim-1 proto-oncogene, serine/threonine kinase | |||||
PMID | Year | Title |
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