PIK3R1
Phosphatidylinositol 3-kinase regulatory subunit alpha
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
biological process | 1 | ||
hub protein | 1 | ||
interacting protein | 1 | ||
transcription factor perturbation | 1 | ||
kinase | 0.99 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Activated NTRK2 signals through PI3K | ||||
Reactome | Activated NTRK3 signals through PI3K | ||||
Reactome | Adaptive Immune System | ||||
Reactome | Antigen activates B Cell Receptor (BCR) leading to generation of second messengers | ||||
Reactome | Axon guidance | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Activated NTRK2 signals through PI3K | ||||
Activated NTRK3 signals through PI3K | ||||
Adaptive Immune System | ||||
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers | ||||
Axon guidance | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | CAFA | |||
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Sequence or structural Similarity (ISS) | BHF-UCL | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
red blood cell distribution width | 3 | 3 | 4 | 92.1 | |||||
mean corpuscular hemoglobin concentration | 1 | 1 | 1 | 81.5 | |||||
mean reticulocyte volume | 1 | 1 | 1 | 77.1 | |||||
lymphocyte count | 2 | 2 | 2 | 73.2 | |||||
body height | 1 | 1 | 1 | 69.2 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
red blood cell distribution width | 4 | 92.1 | |||||
mean corpuscular hemoglobin concentration | 1 | 81.5 | |||||
mean reticulocyte volume | 1 | 77.1 | |||||
lymphocyte count | 2 | 73.2 | |||||
body height | 1 | 69.2 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Macaque | phosphoinositide-3-kinase regulatory subunit 1 | 698996 | ||||||
Mouse | MGI:97583 | 18708 | ||||||
Rat | RGD:3329 | 25513 | ||||||
Dog | phosphoinositide-3-kinase regulatory subunit 1 | VGNC:44560 | 487235 | |||||
Horse | phosphoinositide-3-kinase regulatory subunit 1 | VGNC:21451 | 100050227 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Macaque | phosphoinositide-3-kinase regulatory subunit 1 | |||||
Mouse | ||||||
Rat | ||||||
Dog | phosphoinositide-3-kinase regulatory subunit 1 | |||||
Horse | phosphoinositide-3-kinase regulatory subunit 1 | |||||
PMID | Year | Title |
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