PI4KB
Phosphatidylinositol 4-kinase beta
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
molecular function | 0.91 | ||
protein domain | 0.85 | ||
transcription factor perturbation | 0.84 | ||
disease perturbation | 0.83 | ||
ligand (protein) perturbation | 0.83 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Metabolism | ||||
Reactome | Metabolism of lipids | ||||
Reactome | PI Metabolism | ||||
Reactome | Phospholipid metabolism | ||||
Reactome | Synthesis of PIPs at the Golgi membrane | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Metabolism | ||||
Metabolism of lipids | ||||
PI Metabolism | ||||
Phospholipid metabolism | ||||
Synthesis of PIPs at the Golgi membrane | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
red blood cell distribution width | 2 | 2 | 2 | 66.8 | |||||
vitamin D measurement | 1 | 1 | 1 | 59 | |||||
lymphocyte count | 1 | 1 | 1 | 29 | |||||
gut microbiome measurement | 1 | 1 | 0 | 5.6 | 21.5 | ||||
glomerular filtration rate | 1 | 1 | 1 | 11.4 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
red blood cell distribution width | 2 | 66.8 | |||||
vitamin D measurement | 1 | 59 | |||||
lymphocyte count | 1 | 29 | |||||
gut microbiome measurement | 0 | 5.6 | 21.5 | ||||
glomerular filtration rate | 1 | 11.4 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Macaque | phosphatidylinositol 4-kinase beta | 710104 | ||||||
Mouse | MGI:1334433 | 107650 | ||||||
Rat | RGD:621214 | 81747 | ||||||
Dog | phosphatidylinositol 4-kinase beta | VGNC:44517 | 483196 | |||||
Horse | phosphatidylinositol 4-kinase beta | VGNC:21409 | 100055429 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Macaque | phosphatidylinositol 4-kinase beta | |||||
Mouse | ||||||
Rat | ||||||
Dog | phosphatidylinositol 4-kinase beta | |||||
Horse | phosphatidylinositol 4-kinase beta | |||||
PMID | Year | Title |
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