You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
PGAM4
Probable phosphoglycerate mutase 4

Protein Summary
Description
This intronless gene appears to have arisen from a retrotransposition event, yet it is thought to be an expressed, protein-coding gene. The encoded protein is a member of the phosphoglycerate mutase family, a set of enzymes that catalyze the transfer of a phosphate group from 3-phosphoglycerate to 2-phosphoglycerate. [provided by RefSeq, May 2010]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000458128
  • ENSP00000412189
  • ENSG00000226784

Symbol
  • PGAM3
  • PGAM1
  • PGAM3
  • PGAM-B
  • dJ1000K24.1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
tissue
0.68
protein domain
0.58
cellular component
0.53
microRNA
0.49
tissue sample
0.49


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 25.09   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 80   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 25.09   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 80   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (61)
PGAM2
Tbio
Family:  Enzyme
Novelty:  0.02438933
p_int:  0.999999999
p_wrong:  1e-9
Score:  0.935
Data Source:  BioPlex,STRINGDB
PGK1
Tchem
Family:  Kinase
Novelty:  0.00113494
Score:  0.987
Data Source:  STRINGDB
PGK2
Tbio
Family:  Kinase
Novelty:  0.00832045
Score:  0.977
Data Source:  STRINGDB
GPI
Tbio
Family:  Enzyme
Novelty:  0.00095404
Score:  0.952
Data Source:  STRINGDB
PHGDH
Tchem
Family:  Enzyme
Novelty:  0.00047542
Score:  0.931
Data Source:  STRINGDB
ENO1
Tchem
Family:  Enzyme
Novelty:  0.00109178
Score:  0.929
Data Source:  STRINGDB
TALDO1
Tbio
Family:  Enzyme
Novelty:  0.00208619
Score:  0.917
Data Source:  STRINGDB
TPI1
Tbio
Family:  Enzyme
Novelty:  0.00074652
Score:  0.915
Data Source:  STRINGDB
GLYCTK
Tbio
Family:  Kinase
Novelty:  0.06383854
Score:  0.91
Data Source:  STRINGDB
MINPP1
Tbio
Family:  Enzyme
Novelty:  0.02584444
Score:  0.906
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (7)
Find Similar Targets
Items per page:
1 – 5 of 7
Data Source
Name
Explore in Pharos
Explore in Source
KEGG
Central carbon metabolism in cancer
KEGG
Glycolysis / Gluconeogenesis
KEGG
Carbon metabolism
KEGG
Glucagon signaling pathway
KEGG
Glycine, serine and threonine metabolism
Name
Explore in Pharos
Explore in Source
Central carbon metabolism in cancer
Glycolysis / Gluconeogenesis
Carbon metabolism
Glucagon signaling pathway
Glycine, serine and threonine metabolism
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (2)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
body height
1
1
1
79.8
mean platelet volume
1
1
1
61
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
body height
1
79.8
mean platelet volume
1
61
IDG Resources
No IDG generated resources found
Orthologs (2)
1 – 2 of 2
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Xenopus
phosphoglycerate mutase 1
XB-GENE-1007742
100144939
Zebrafish
ZDB-GENE-030131-1827
323107
Species
Name
OMA
EggNOG
Inparanoid
Xenopus
phosphoglycerate mutase 1
Zebrafish
Publication Statistics
PubMed Score 25.09
PubMed score by year
PubTator Score 10.08
PubTator score by year
loading...
Related Publications
Items per page:
0 of 0
PMID
Year
Title