Tbio PGAM4 Probable phosphoglycerate mutase 4

Protein Summary

Description

This intronless gene appears to have arisen from a retrotransposition event, yet it is thought to be an expressed, protein-coding gene. The encoded protein is a member of the phosphoglycerate mutase family, a set of enzymes that catalyze the transfer of a phosphate group from 3-phosphoglycerate to 2-phosphoglycerate. [provided by RefSeq, May 2010]

Uniprot Accession IDs

• Q8N0Y7
• Q5JPN2
• Q8NI24
• Q8NI25
• Q8NI26

Gene Name

• PGAM4

Ensembl ID

• ENST00000458128
• ENSP00000412189
• ENSG00000226784

Symbol

• PGAM3
• PGAM1
• PGAM3
• PGAM-B
• dJ1000K24.1

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
tissue	0.68
protein domain	0.58
cellular component	0.53
microRNA	0.49
tissue sample	0.49

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 33.29   (req: < 5)

Gene RIFs: 2   (req: <= 3)

Antibodies: 80   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 33.29   (req: >= 5)

Gene RIFs: 2   (req: > 3)

Antibodies: 80   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0