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Tbio
PEX11G
Peroxisomal membrane protein 11C

Protein Summary
Description
Promotes membrane protrusion and elongation on the peroxisomal surface. The protein encoded by this gene is a member of the PEX11 family. This family is reported to regulate the number and size of peroxisomes in evolutionarily distant organisms. The protein encoded by this gene may induce clustering of peroxisomes. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jul 2012]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000221480
  • ENSP00000221480
  • ENSG00000104883
  • ENST00000593942
  • ENSP00000472216

Symbol
  • PEX11C
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.88
cell type or tissue
0.84
cellular component
0.64
tissue sample
0.62
cell line
0.48


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.37   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 59   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.37   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 59   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (48)
PEX11B
Tbio
Novelty:  0.04285427
Score:  0.975
Data Source:  STRINGDB
PEX11A
Tbio
Novelty:  0.01387985
Score:  0.971
Data Source:  STRINGDB
PEX3
Tbio
Novelty:  0.01171119
Score:  0.859
Data Source:  STRINGDB
SLC25A17
Tbio
Family:  Transporter
Novelty:  0.00601179
Score:  0.854
Data Source:  STRINGDB
PEX13
Tbio
Novelty:  0.01777214
Score:  0.841
Data Source:  STRINGDB
PEX10
Tbio
Novelty:  0.0174463
Score:  0.822
Data Source:  STRINGDB
PEX16
Tbio
Novelty:  0.03119723
Score:  0.799
Data Source:  STRINGDB
PEX12
Tbio
Novelty:  0.02252744
Score:  0.796
Data Source:  STRINGDB
PEX5
Tbio
Novelty:  0.00560901
Score:  0.782
Data Source:  STRINGDB
PEX7
Tbio
Novelty:  0.01487923
Score:  0.768
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (5)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
electrocardiography
1
1
20
58.4
mean platelet volume
1
1
1
53.7
eosinophil percentage of leukocytes
1
1
1
49.5
left ventricular structural measurement
3
1
3
49.5
opioid overdose severity measurement
1
1
1
31.4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
electrocardiography
20
58.4
mean platelet volume
1
53.7
eosinophil percentage of leukocytes
1
49.5
left ventricular structural measurement
3
49.5
opioid overdose severity measurement
1
31.4
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
peroxisomal biogenesis factor 11 gamma
VGNC:2290
455654
Macaque
peroxisomal biogenesis factor 11 gamma
703198
Mouse
MGI:1920905
69129
Rat
RGD:1307070
288369
Dog
peroxisomal biogenesis factor 11 gamma
VGNC:44428
484992
Species
Name
OMA
EggNOG
Inparanoid
Chimp
peroxisomal biogenesis factor 11 gamma
Macaque
peroxisomal biogenesis factor 11 gamma
Mouse
Rat
Dog
peroxisomal biogenesis factor 11 gamma
Publication Statistics
PubMed Score 3.37
PubMed score by year
PubTator Score 1.08
PubTator score by year
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Related Publications
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PMID
Year
Title