Tbio PECR Peroxisomal trans-2-enoyl-CoA reductase

Protein Summary

Description

Participates in chain elongation of fatty acids. Has no 2,4-dienoyl-CoA reductase activity.

Uniprot Accession IDs

• Q9BY49
• B2RE42
• Q53TC4
• Q6IAK9
• Q9NRD4
• Q9NY60
• Q9P1A4
• TERP

Gene Name

• PECR

Ensembl ID

• ENST00000265322
• ENSP00000265322
• ENSG00000115425

Symbol

• SDR29C1
• TERP
• DCRRP
• PVIARL
• HPDHASE
• SDR29C1
• HSA250303

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
transcription factor perturbation	0.94
virus perturbation	0.92
kinase perturbation	0.81
histone modification site profile	0.8
interacting protein	0.77

Protein Classes

PANTHER Classes

Protein / Oxidoreductase / Reductase / Peroxisomal Trans-2-enoyl-coa Reductase

Protein / Oxidoreductase / Dehydrogenase / Peroxisomal Trans-2-enoyl-coa Reductase

DTO Classes

Protein / Enzyme / Oxidoreductase / Dehydrogenase / Peroxisomal Trans-2-enoyl-coa Reductase

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 101.71   (req: < 5)

Gene RIFs: 4   (req: <= 3)

Antibodies: 159   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 101.71   (req: >= 5)

Gene RIFs: 4   (req: > 3)

Antibodies: 159   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 7

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0