PDE9A
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A
You are using an outdated browser. Please upgrade your browser to improve your experience.
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
kinase perturbation | 0.76 | ||
PubMedID | 0.73 | ||
disease | 0.63 | ||
transcription factor binding site profile | 0.59 | ||
protein domain | 0.58 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Hemostasis | ||||
Reactome | Nitric oxide stimulates guanylate cyclase | ||||
Reactome | Platelet homeostasis | ||||
Reactome | cGMP effects | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Hemostasis | ||||
Nitric oxide stimulates guanylate cyclase | ||||
Platelet homeostasis | ||||
cGMP effects | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | IntAct | |||
Traceable Author Statement (TAS) | ProtInc | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
hematocrit | 2 | 2 | 2 | 77.8 | |||||
hemoglobin measurement | 2 | 2 | 2 | 73.4 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
hematocrit | 2 | 77.8 | |||||
hemoglobin measurement | 2 | 73.4 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | phosphodiesterase 9A | VGNC:1134 | 474020 | |||||
Macaque | phosphodiesterase 9A | 100301991 | ||||||
Mouse | MGI:1277179 | 18585 | ||||||
Rat | RGD:621035 | 191569 | ||||||
Dog | phosphodiesterase 9A | VGNC:44367 | 611022 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | phosphodiesterase 9A | |||||
Macaque | phosphodiesterase 9A | |||||
Mouse | ||||||
Rat | ||||||
Dog | phosphodiesterase 9A | |||||
PMID | Year | Title |
---|